束状形成α-螺旋肽-树枝状分子杂化物
Bundle-forming α-helical peptide-dendron hybrid.
作者信息
Marine Jeannette E, Song Shuang, Liang Xiaoli, Watson Matthew D, Rudick Jonathan G
机构信息
Department of Chemistry, Stony Brook University, Stony Brook, NY 11794, USA.
出版信息
Chem Commun (Camb). 2015 Oct 1;51(76):14314-7. doi: 10.1039/c5cc05468k. Epub 2015 Aug 13.
Abstract
Peptides and dendrons are enticing building blocks from which to construct hybrid macromolecules because each can be prepared as monodisperse and sequence defined materials. Folding and assembly properties designed into the amino acid sequence of a peptide-dendron hybrid manifest in the formation of a dendronized bundle of α-helices.
摘要
肽和树枝状分子是构建杂化大分子的诱人构件，因为它们都可以制备成单分散且序列明确的材料。设计到肽-树枝状分子杂化物氨基酸序列中的折叠和组装特性表现为形成树枝状化的α-螺旋束。
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