大肠杆菌MG1655通过细胞周期调节其磷脂组成。

E. coli MG1655 modulates its phospholipid composition through the cell cycle.

作者信息

Furse Samuel, Wienk Hans, Boelens Rolf, de Kroon Anton I P M, Killian J Antoinette

机构信息

Membrane Biochemistry and Biophysics, Department of Chemistry, Universiteit Utrecht, Kruytgebouw, Padualaan 8, 3584 CH Utrecht, The Netherlands.

NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Department of Chemistry, Universiteit Utrecht, Padualaan 8, 3584 CH Utrecht, The Netherlands.

出版信息

FEBS Lett. 2015 Sep 14;589(19 Pt B):2726-30. doi: 10.1016/j.febslet.2015.07.043. Epub 2015 Aug 10.

DOI:10.1016/j.febslet.2015.07.043

PMID:26272829

Abstract

This paper describes a study of the phospholipid profile of Escherichia coli MG1655 cultures at the B and D periods of the cell cycle. The results indicate that the phosphatidyl glycerol fraction grows relatively rapidly and that the size of the cardiolipin (CL) fraction does not grow at all during cell elongation. This is consistent with observations that CL is located preferentially at the poles of E. coli. It also suggests that lipid production is controlled as a function of the cell cycle.

摘要

本文描述了一项关于大肠杆菌MG1655培养物在细胞周期的B期和D期磷脂谱的研究。结果表明，磷脂酰甘油部分增长相对较快，而心磷脂（CL）部分的大小在细胞伸长过程中根本没有增长。这与CL优先位于大肠杆菌两极的观察结果一致。这也表明脂质产生是作为细胞周期的函数受到控制的。