[二甲基乙酰胺和二甲基亚砜在适度低温下保存血小板的冷冻保护特性的比较研究]
[A comparative study of the cryoprotective properties of dimethylacetamide and dimethyl sulfoxide in preserving thrombocytes at moderately low temperatures].
作者信息
Azovskaia S A, Sukhanov Iu S, Zhukovskaia N L, Konoplina L A
出版信息
Gematol Transfuziol. 1989 Dec;34(12):18-21.
Comparative characteristics of cryoprotective properties of dimethylacetamide and dimethyl sulfoxide (DMAC and DMSO, respectively), used for freezing and storage of platelets at -80 degrees C, have been presented. It is shown that with the studied final concentrations of the cryoprotectors (5% of DMSO, 2.5% of DMAC), solutions containing DMSO display higher cryoprotective properties. Positive effect of autoplasma in the mixture with the platelet-protecting solution has been manifest in the maintaining of the functional properties of platelets after defrosting.
本文介绍了用于在-80℃下冷冻和储存血小板的二甲基乙酰胺和二甲基亚砜（分别为DMAC和DMSO）的冷冻保护特性的比较特征。结果表明，在所研究的冷冻保护剂最终浓度（5%的DMSO，2.5%的DMAC）下，含有DMSO的溶液显示出更高的冷冻保护特性。自体血浆与血小板保护溶液混合后的积极作用在解冻后血小板功能特性的维持中得以体现。
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