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[实验性静脉注射超分散铁磁性颗粒过程中血液的形态功能状态]

[The morphofunctional status of the blood during the experimental intravenous administration of ultradispersed ferromagnetic particles].

作者信息

Volkonskiĭ V A

出版信息

Gematol Transfuziol. 1989 Dec;34(12):37-40.

PMID:2628153
Abstract

In experiments on rats it has been shown that a single infusion of ultradispersed ferromagnetic particles (size from 0.2 to 1 micron) in a dose of 50 mg/kg leads to an increase in hemoglobin level, red blood cell and leucocyte content, to a growth of blood coagulation time and plasma fibrinolytic activity in the animals' blood, as well as to a rise in the level of neutrophil phagocytic reactions. A single infusion of magnetite particles of similar size, in a dose of 50 mg/kg, was not attended by the above changes, except for an increase in the neutrophil functional activity.

摘要

在对大鼠的实验中已表明,以50毫克/千克的剂量单次注入超分散铁磁性颗粒(尺寸为0.2至1微米)会导致动物血液中血红蛋白水平、红细胞和白细胞含量增加,血液凝固时间延长,血浆纤维蛋白溶解活性增强,以及中性粒细胞吞噬反应水平升高。以50毫克/千克的剂量单次注入类似尺寸的磁铁矿颗粒,除了中性粒细胞功能活性增加外,未出现上述变化。

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