Ray Animikh, Mandal Abhirup, Joseph Mary, Mitra Ashim K
University of Missouri- Kansas City, Kansas City, MO 64108, USA.
Recent Pat Drug Deliv Formul. 2016;10(1):11-23. doi: 10.2174/1872211309666150818110846.
Cancer is a major malignancy which has claimed numerous lives worldwide. Despite huge resources being utilized to develop cancer therapeutics, no effective cure has been found so far. Hence there is a need to look at emerging technologies for a solution. Nanoparticle is one such technology that has become feasible and popular in the past few years. Though, it has not emerged as a drug delivery platform of choice for cancer therapeutics it has shown enormous promise. Different types of materials such as polymer, lipid, magnet, metal based nanoparticles have been developed to enhance the effectiveness of current treatment. This manuscript will review different aspects of nanoparticles and recent research advances and patents for treatment of cancer.
癌症是一种主要的恶性肿瘤,在全球范围内夺走了无数人的生命。尽管投入了大量资源来开发癌症治疗方法,但迄今为止尚未找到有效的治愈方法。因此,有必要探索新兴技术来寻求解决方案。纳米颗粒就是这样一种在过去几年中变得可行且流行的技术。虽然它尚未成为癌症治疗首选的药物递送平台,但已显示出巨大的潜力。人们已经开发出不同类型的材料,如聚合物、脂质、磁性、金属基纳米颗粒,以提高当前治疗的效果。本文将综述纳米颗粒的不同方面以及癌症治疗的最新研究进展和专利。