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[Effect of work in hot shops at the coke-processing plant on the liver and gastrointestinal tract].

作者信息

Pokrzywnicki W, Sroczyński J, Wieja A, Dwornicki M

机构信息

Z Katedry i Kliniki Chorób Wewnetrznych i Zawodowych Sl. AM w Zabrzu.

出版信息

Med Pr. 1989;40(5):315-20.

PMID:2628699
Abstract

253 cooking plant workers employed for 5 years were examined. 207 of them were exposed to very high concentrations of BaP and tar substances, as well as to benzene, its homologues and CO at concentrations not exceeding MAC values. In 20% of the examined workers of the baking ovens department exposed to very high BaP concentrations an abnormal activity of marker enzymes was demonstrated, while in 63% of workers C-14 aminopyrine test was pathologic. These facts indicate that hepatocyte microsomal injury may be affected by toxic effects of BaP. The stool occult blood test was positive in 4% of subjects, which resulted from some non-malignant diseases of the digestive system.

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