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[一名2岁男孩的阵发性冷血红蛋白尿症]

[Paroxysmal cold hemoglobinuria in a 2-year-old boy].

作者信息

Bohnhorst B, Krull F, Hoyer P F

机构信息

Abteilung Kinderheilkunde II, Kinderklinik der Medizinischen Hochschule, Hannover.

出版信息

Monatsschr Kinderheilkd. 1989 Dec;137(12):785-6.

PMID:2628748
Abstract

We report the case of a two-year-old boy, who presented with two episodes of severe abdominal pain and consecutive macrohematuria after he had been outside the house at very low temperatures. The cause of this was found to be acute hemolytic anemia with hemoglobinuria, induced by a cold reacting Donath-Landsteiner autoantibody. After a few days parameters of hemolysis had normalized, hemoglobin levels were within the normal range after 4 weeks. Eight months later the Donath-Landsteiner autoantibody could not be detected any more, the boy is healthy since then.

摘要

我们报告了一名两岁男孩的病例,他在极低温度下外出后出现了两次严重腹痛和连续性肉眼血尿。发现病因是由冷反应性多纳-兰斯泰纳自身抗体诱发的急性溶血性贫血伴血红蛋白尿。几天后溶血参数恢复正常,4周后血红蛋白水平在正常范围内。8个月后不再检测到多纳-兰斯泰纳自身抗体,此后该男孩一直健康。

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