Bell Cameron, Slim Jessica, Flaten Hanna K, Lindberg Gordon, Arek Wiktor, Monte Andrew A
University of Colorado Hospital Burn Center, Aurora, CO, USA.
Denver Health Emergency Medicine Residency, Denver Health & Hospital Authority, Denver, CO, USA.
J Med Toxicol. 2015 Dec;11(4):422-5. doi: 10.1007/s13181-015-0501-0.
Butane hash oil (BHO), also known as "amber," "dab," "glass," "honey," "shatter," or "wax," is a potent marijuana concentrate, containing up to 90 % tetrahydrocannabinol (THC). BHO is easily manufactured using highly volatile butane as a solvent. Our objective was to characterize hydrocarbon burns associated with BHO manufacture in Colorado. This was a cross-sectional study utilizing the National Burn Repository to capture all hydrocarbon burns reported to the local burn center from January 1st, 2008, through August 31st, 2014. We abstracted demographic and clinical variables from medical records for patients admitted for hydrocarbon burns associated with butane hash oil extraction. Twenty-nine cases of BHO burns were admitted to the local burn center during the study period. Zero cases presented prior to medical liberalization, 19 (61.3 %) during medical liberalization (Oct 2009-Dec 2013), and 12 (38.7 %) in 2014 since legalization. The majority of cases were Caucasian (72.4 %) males (89.7 %). Median age was 26 (range 15-58). The median total-body-surface-area (TBSA) burn size was 10 % (TBSA range 1-90 %). Median length of hospital admission was 10 days. Six required intubation for airway protection (21 %). Nineteen required skin grafting, eight wound care only, one required surgical fracture repair, and one required surgical debridement. Hydrocarbon burns associated with hash oil production have increased since the liberalization of marijuana policy in Colorado. A combination of public health messaging, standardization of manufacturing processes, and worker safety regulations are needed to decrease the risks associated with BHO production.
丁烷大麻油(BHO),也被称为“琥珀”“小块浓缩大麻”“玻璃”“蜂蜜”“碎片”或“蜡”,是一种效力强劲的大麻浓缩物,含有高达90%的四氢大麻酚(THC)。BHO很容易用极易挥发的丁烷作为溶剂制造出来。我们的目的是描述科罗拉多州与BHO制造相关的烃类烧伤情况。这是一项横断面研究,利用国家烧伤资料库收集2008年1月1日至2014年8月31日期间向当地烧伤中心报告的所有烃类烧伤病例。我们从因与丁烷大麻油提取相关的烃类烧伤而入院的患者病历中提取了人口统计学和临床变量。在研究期间,有29例BHO烧伤患者被收治到当地烧伤中心。在医疗自由化之前无病例,在医疗自由化期间(2009年10月至2013年12月)有19例(61.3%),自合法化后的2014年有12例(38.7%)。大多数病例为白种人(72.4%)男性(89.7%)。中位年龄为26岁(范围15 - 58岁)。中位全身表面积(TBSA)烧伤面积为10%(TBSA范围1 - 90%)。中位住院时间为10天。6例需要气管插管以保护气道(21%)。19例需要植皮,8例仅需伤口护理,1例需要手术修复骨折,1例需要手术清创。自科罗拉多州大麻政策自由化以来,与大麻油生产相关的烃类烧伤有所增加。需要综合采取公共卫生宣传、制造工艺标准化和工人安全法规等措施来降低与BHO生产相关的风险。