Hoffmann Michael, MacCarthy Sarah, Batson Ashley, Crawford-Roberts Ann, Rasanathan Jennifer, Nunn Amy, Silva Luis Augusto, Dourado Ines
a Brown University School of Public Health and the Miriam Hospital , 121 South Main St. Suite 810, Providence , RI 02912 , USA.
b RAND Corporation , 1776 Main Street, Santa Monica , CA 90407 , USA.
AIDS Care. 2016;28(1):57-62. doi: 10.1080/09540121.2015.1062462. Epub 2015 Aug 20.
Global and national HIV/AIDS policies utilize the care cascade to emphasize the importance of continued engagement in HIV services from diagnosis to viral suppression. Several studies have documented barriers that men experience in accessing services at specific stages of care, but few have analyzed how these barriers operate along the care cascade. Brazil offers a unique setting for analyzing barriers to HIV care because it is a middle-income country with a large HIV epidemic and free, universal access to HIV/AIDS services. Semi-structured interviews were conducted in 2011 with HIV-infected men (n = 25) receiving care at the only HIV/AIDS state reference center in Salvador, Brazil, the third largest city in the country. Interviews were transcribed and coded for analysis. Researchers identified barriers to services along the care cascade: health service-related obstacles (poor-quality care, lengthy wait times, and drug supply problems); psychosocial and emotional challenges (fear of disclosure and difficulty accepting HIV diagnosis); indirect costs (transportation and absenteeism at work or school); low perceived risk of HIV; and toxicity and complexity of antiretroviral drug (ARV) regimens. The stages of the care cascade interrupted by each barrier were also identified. Most barriers affected multiple, and often all, stages of care, while toxicity and complexity of ARV regimens was only present at a single care stage. Efforts to eliminate more prevalent barriers have the potential to improve care continuity at multiple stages. Going forward, assessing the relative impact of barriers along one's entire care trajectory can help tailor improvements in service provision, facilitate achievement of viral suppression, and improve access to life-saving testing, treatment, and care.
全球和国家的艾滋病毒/艾滋病政策利用治疗级联来强调从诊断到病毒抑制持续接受艾滋病毒服务的重要性。几项研究记录了男性在特定治疗阶段获得服务时遇到的障碍,但很少有研究分析这些障碍在治疗级联过程中是如何起作用的。巴西为分析艾滋病毒治疗障碍提供了一个独特的环境,因为它是一个中等收入国家,艾滋病毒疫情严重,且能免费普遍获得艾滋病毒/艾滋病服务。2011年,对在巴西第三大城市萨尔瓦多唯一的艾滋病毒/艾滋病国家参考中心接受治疗的25名艾滋病毒感染男性进行了半结构式访谈。访谈内容被转录并编码以便分析。研究人员确定了治疗级联过程中的服务障碍:与卫生服务相关的障碍(护理质量差、等待时间长和药品供应问题);心理社会和情感挑战(害怕暴露和难以接受艾滋病毒诊断);间接成本(交通以及工作或学校缺勤);对艾滋病毒的低感知风险;以及抗逆转录病毒药物(ARV)治疗方案的毒性和复杂性。还确定了每个障碍所打断的治疗级联阶段。大多数障碍影响多个,且往往是所有治疗阶段,而ARV治疗方案的毒性和复杂性仅出现在单一治疗阶段。消除更普遍障碍的努力有可能在多个阶段改善治疗的连续性。展望未来,评估一个人整个治疗轨迹上障碍的相对影响有助于调整服务提供方面的改进,促进实现病毒抑制,并改善获得挽救生命的检测、治疗和护理的机会。