Jissy A K, Datta Ayan
†School of Chemistry, Indian Institute of Science Education and Research Thiruvananthapuram, CET Campus, Thiruvananthapuram-695016, Kerala, India.
‡Department of Spectroscopy, Indian Association for the Cultivation of Science, Jadavpur -700032, West Bengal, India.
J Phys Chem Lett. 2013 Mar 21;4(6):1018-22. doi: 10.1021/jz400263y. Epub 2013 Mar 13.
Recently, inorganic double-helical structures based on simple lithium and phosphorus salts have been demonstrated. We have analyzed the nature of bonding in these double helices of LinPn (n = 7-9). Similar to DNA, noncovalent interactions and cooperativity play an important role in stabilizing the inorganic double helices. Cooperativity imparts an additional stabilization of 4.5 to 10.1 kcal/mol per Li-P pair. In addition, the ionicity of Li-P units further augments the stability of these inorganic double-helix structures in contrast with the canonical base pairs in DNA, where noncovalent interactions determine the duplex stability. Unwinding is shown to be unfavorable, and cleavage of a few edge Li-P bonds leads to spontaneous self-healing into the intact double-helix tract.
最近，基于简单锂盐和磷酸盐的无机双螺旋结构已被证实。我们分析了LinPn（n = 7 - 9）这些双螺旋中的键合性质。与DNA类似，非共价相互作用和协同作用在稳定无机双螺旋中起着重要作用。协同作用使每个Li - P对额外稳定4.5至10.1千卡/摩尔。此外，与DNA中的典型碱基对不同，Li - P单元的离子性进一步增强了这些无机双螺旋结构的稳定性，在DNA中，非共价相互作用决定双链稳定性。结果表明解旋是不利的，少数边缘Li - P键的断裂会导致自发自我修复为完整的双螺旋片段。
