Fernández Alonso Ana M, Chedraui Peter, Pérez-López Faustino R
a Department of Obstetrics and Gynecology , Hospital Torrecárdenas , Almeria , Spain .
b Facultad de Ciencias Médicas , Institute of Biomedicine, Research Area for Women's Health, Universidad Católica de Santiago de Guayaquil , Guayaquil , Ecuador .
Gynecol Endocrinol. 2015;31(9):715-9. doi: 10.3109/09513590.2015.1034099. Epub 2015 Aug 17.
To assess the risk of obstructive sleep apnea-hypopnea syndrome (OSAHS) and related factors at the end of pregnancy using the Berlin questionnaire.
A total of 367 women at the end of pregnancy (median gestational age 39 weeks) were interviewed with the Berlin questionnaire and a general survey containing maternal socio-demographic and anthropometric information. Neonatal outcome data were also assessed.
Median age for the whole sample was 31 years. According to the Berlin questionnaire, 39.8% were positive for high risk of OSAHS. Upon bivariate analysis, higher risk of OSAHS was significantly related to church attendance, and higher pre-pregnancy body mass index (BMI), current BMI, weight, neck and arm circumference and systolic blood pressure at survey. Logistic regression analysis found that higher maternal pre-pregnancy BMI (OR 2.71 95% CI 1.84-4.00, p < 0.0001) and higher maternal weight at survey (OR 3.02, 95% CI 1.78-5.17, p < 0.0001) were significantly related to a higher risk of OSAHS.
The risk of OSAHS is relatively high at the end of pregnancy and related to a higher pre-pregnancy BMI and higher maternal weight at survey. Further studies are needed to confirm our results with a diagnostic tool, such as polysomnography or another similar yet less complicated to carry out procedure.
使用柏林问卷评估妊娠末期阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的风险及相关因素。
对367名妊娠末期妇女(中位孕周39周)进行了柏林问卷访谈,并进行了一项包含产妇社会人口统计学和人体测量学信息的综合调查。还评估了新生儿结局数据。
整个样本的中位年龄为31岁。根据柏林问卷,39.8%的人OSAHS高风险呈阳性。经双变量分析,OSAHS较高风险与参加教会活动、孕前较高体重指数(BMI)、当前BMI、体重、颈部和手臂周长以及调查时的收缩压显著相关。逻辑回归分析发现,较高的产妇孕前BMI(OR 2.71,95%CI 1.84 - 4.00,p < 0.0001)和调查时较高的产妇体重(OR 3.02,95%CI 1.78 - 5.17,p < 0.0001)与较高的OSAHS风险显著相关。
妊娠末期OSAHS风险相对较高,且与较高的孕前BMI和调查时较高的产妇体重有关。需要进一步研究以使用多导睡眠图或另一种类似但实施起来较不复杂的程序等诊断工具来证实我们的结果。