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葡萄状神经囊尾蚴病的脑脊液分析

Analysis of cerebrospinal fluid in racemose form of neurocysticercosis.

作者信息

Bazan Rodrigo, Odashima Newton Satoru, Luvizutto Gustavo José, Hamamoto Filho Pedro Tadao, Zanini Marco Antonio, Takayanagui Osvaldo Massaiti

机构信息

Departamento de Neurologia, Psicologia e Psiquiatria, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, BR.

Departamento de Neurociências e Ciências do Comportamento, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirao Preto, SP, BR.

出版信息

Arq Neuropsiquiatr. 2015 Oct;73(10):852-5. doi: 10.1590/0004-282X20150120. Epub 2015 Aug 18.

Abstract

The present work aimed to evaluate the pattern of CSF alterations in patients diagnosed with neurocysticercosis (NCC) in racemose form.Method This is a retrospective cohort study of patients with diagnosis of NCC in racemose form. CSF samples from 26 patients were analyzed. After patient-chart analysis was performed descriptive analysis of case studies and comparison between sexes in relation to variables were obtained with CSF by Mann-Whitney and Student's t-tests.Results The sexes did not differ statistically when compared to pleocytosis in CSF. Eosinophils were present in 31% in samples while the ELISA test presented 80% sensitivity in this case series. Of the patient total, 24 presented a meningitis pattern with lymphocytic predominance.Conclusion There was no difference in inflammatory pattern between the sexes, with predominance of lymphocytic meningitis and 80% sensitivity by ELISA test of CSF patients with racemose form of NCC.

摘要

本研究旨在评估诊断为葡萄状神经囊尾蚴病(NCC)患者的脑脊液改变模式。方法:这是一项对诊断为葡萄状NCC患者的回顾性队列研究。分析了26例患者的脑脊液样本。在进行患者病历分析后,对病例研究进行描述性分析,并通过Mann-Whitney检验和学生t检验对脑脊液相关变量进行性别间比较。结果:脑脊液中细胞增多时,男女之间无统计学差异。样本中31%存在嗜酸性粒细胞,而在本病例系列中ELISA试验的敏感性为80%。在所有患者中,24例呈现以淋巴细胞为主的脑膜炎模式。结论:男女之间的炎症模式无差异,以淋巴细胞性脑膜炎为主,葡萄状NCC患者脑脊液ELISA试验的敏感性为80%。

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