Linchevskaia A A, Kondrat'eva L A
Vopr Med Khim. 1989 Nov-Dec;35(6):36-9.
Under conditions of hypothermia intensification of lipid peroxidation, activation of phospholipase A2 and distinct alteration in lipid metabolism were found in rat erythrocyte membranes. Alterations in membrane composition correlated with a decrease in erythrocyte resistance and their stability to deformation. Erythrocytes with altered structure-functional properties might be responsible for hemodynamic impairments of tissues.
在体温过低的情况下,在大鼠红细胞膜中发现脂质过氧化加剧、磷脂酶A2激活以及脂质代谢明显改变。膜成分的改变与红细胞抵抗力及其对变形的稳定性降低相关。结构 - 功能特性改变的红细胞可能是组织血液动力学损伤的原因。