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[低温对白化病大鼠红细胞膜结构功能特性的影响]

[The effect of hypothermia on the structural-functional properties of erythrocyte membranes in albino rats].

作者信息

Linchevskaia A A, Kondrat'eva L A

出版信息

Vopr Med Khim. 1989 Nov-Dec;35(6):36-9.

PMID:2629239
Abstract

Under conditions of hypothermia intensification of lipid peroxidation, activation of phospholipase A2 and distinct alteration in lipid metabolism were found in rat erythrocyte membranes. Alterations in membrane composition correlated with a decrease in erythrocyte resistance and their stability to deformation. Erythrocytes with altered structure-functional properties might be responsible for hemodynamic impairments of tissues.

摘要

在体温过低的情况下,在大鼠红细胞膜中发现脂质过氧化加剧、磷脂酶A2激活以及脂质代谢明显改变。膜成分的改变与红细胞抵抗力及其对变形的稳定性降低相关。结构 - 功能特性改变的红细胞可能是组织血液动力学损伤的原因。

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