Departments of Pediatrics and Neurology, Children's Hospital Colorado, University of Colorado at Denver, Aurora, Colorado, U.S.A.
Department of Neuroscience, Bambino Gesù Children's Hospital, Rome, Italy.
Epilepsia. 2015 Oct;56(10):1482-5. doi: 10.1111/epi.13109. Epub 2015 Aug 21.
In epileptic encephalopathy, the seizures and interictal epileptiform activity create additional neurocognitive dysfunction beyond that due to the underlying etiology. Treatment leading to a reduction in seizures or interictal abnormalities may help improve neurocognitive function in these situations. The focus of our discussion is reviewing data that support the concept that treatment can impact outcome independent of the etiology in some cases.
在癫痫性脑病中，发作和发作间期痫样放电除了由潜在病因引起的以外，还会导致额外的神经认知功能障碍。导致发作减少或发作间期异常减少的治疗可能有助于改善这些情况下的神经认知功能。我们讨论的重点是回顾支持以下概念的数据，即在某些情况下，治疗可以独立于病因影响结局。
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