von Kemp K, Herregodts P, Duynslaeger L, Deleu D, Bruyland M, Cham B
Acta Clin Belg. 1989;44(6):383-7. doi: 10.1080/17843286.1989.11718047.
Chronic intramuscular injections, particularly of narcotic analgesics, are an uncommon cause of myopathy. We report two patients with pentazocine- and meperidine-related myopathy. Narcotic-induced muscular fibrosis and contractures must be considered in patients with a pattern of muscle involvement that does not conform to any recognized myopathy, but allows for self-administration of injections. Trauma due to needle puncture, repetitive infections and a local myotoxic effect of the drugs probably contribute to these lesions.
长期肌肉注射，尤其是麻醉性镇痛药的注射，是肌病的一种罕见病因。我们报告了两例与喷他佐辛和哌替啶相关的肌病患者。对于肌肉受累模式不符合任何公认肌病，但存在自行注射可能性的患者，必须考虑麻醉药引起的肌肉纤维化和挛缩。针刺创伤、反复感染以及药物的局部肌毒性作用可能促成了这些病变。
