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白内障超声乳化术后前房内晶状体碎片残留的临床特征与转归

Clinical Features and Outcomes of Retained Lens Fragments in the Anterior Chamber After Phacoemulsification.

作者信息

Zavodni Zachary J, Meyer Jay J, Kim Terry

机构信息

Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina.

Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina.

出版信息

Am J Ophthalmol. 2015 Dec;160(6):1171-1175.e1. doi: 10.1016/j.ajo.2015.08.019. Epub 2015 Aug 20.

DOI:10.1016/j.ajo.2015.08.019
PMID:26299538
Abstract

PURPOSE

To review the clinical features, treatments, and outcomes of patients with retained lens fragments in the anterior chamber after phacoemulsification with an intact posterior capsule.

DESIGN

Retrospective, interventional case series.

METHODS

setting: Duke University Eye Center.

STUDY POPULATION

Fifty-four eyes of 54 patients with a diagnosis of retained lens fragment in the anterior chamber following otherwise uncomplicated phacoemulsification cataract surgery. Patient demographics, clinical examination findings, ocular biometry measurements, treatment received, and pre- and post-lens fragment removal visual acuity were recorded.

MAIN OUTCOME MEASURES

Corneal edema, time to surgical extraction of lens fragment, and visual acuity.

RESULTS

All lens fragments were located in the inferior angle or the inferior anterior chamber, with 13% of cases requiring gonioscopy for diagnosis. Fifty-six percent of eyes had associated corneal edema, most often located inferiorly. Forty-four percent of patients were initially managed medically, but in all 54 cases the lens fragment was eventually removed surgically. The mean time to removal of the lens fragment from the date of cataract surgery was 70 days (range 1 day-30 months). Five patients had corneal edema that did not resolve following fragment extraction and 3 eventually received an endothelial keratoplasty. Best-corrected visual acuity improved from an average of 20/51 before lens fragment removal to 20/28 after surgical extraction (P < .00001).

CONCLUSIONS

Corneal edema is common in the setting of retained lens fragments and can evolve to corneal decompensation requiring transplantation. Inferior corneal edema, in particular, should alert the practitioner to possible retained lens fragment. Surgical removal of retained lens fragments should be considered at the time of diagnosis.

摘要

目的

回顾在超声乳化白内障吸除术中后囊完整但前房内残留晶状体碎片患者的临床特征、治疗方法及预后。

设计

回顾性干预性病例系列研究。

方法

地点:杜克大学眼科中心。

研究对象

54例患者的54只眼,诊断为在无并发症的超声乳化白内障手术后前房内残留晶状体碎片。记录患者人口统计学资料、临床检查结果、眼部生物测量数据、接受的治疗以及晶状体碎片取出术前和术后的视力。

主要观察指标

角膜水肿、晶状体碎片手术取出时间和视力。

结果

所有晶状体碎片均位于下角或下前房,13%的病例需要房角镜检查以明确诊断。56%的眼伴有角膜水肿,最常见于下方。44%的患者最初接受药物治疗,但在所有54例病例中,晶状体碎片最终均通过手术取出。从白内障手术日期至晶状体碎片取出的平均时间为70天(范围1天至30个月)。5例患者在碎片取出后角膜水肿未消退,3例最终接受了内皮角膜移植术。最佳矫正视力从晶状体碎片取出前的平均20/51提高到手术取出后的20/28(P < .00001)。

结论

在前房残留晶状体碎片的情况下角膜水肿很常见,且可发展为需要移植的角膜失代偿。尤其是下方角膜水肿应提醒医生注意可能存在残留晶状体碎片。在诊断时应考虑手术取出残留的晶状体碎片。

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