Schewe Jens-Christian, Kappler Jochen, Heister Ulrich, Weber Stefan Udo, Diepenseifen Christian Jens, Frings Benjamin, Hoeft Andreas, Fischer Matthias
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
Department of Anaesthesiology and Intensive Care Medicine, University Hospital Bonn, Sigmund-Freud-Street 25, 53105 Bonn, Germany.
Resuscitation. 2015 Nov;96:232-8. doi: 10.1016/j.resuscitation.2015.07.025. Epub 2015 Aug 22.
Patient outcome after out of hospital cardiac arrest (OHCA) depends on the cardiopulmonary resuscitation (CPR) performance and might also be influenced by organisation of the emergency medical service (EMS) and implementation of guidelines.
To assess the rate of return of spontaneous circulation (ROSC) after cardiac arrest to the predicted rate by the ROSC after cardiac arrest (RACA) score over a 15-year period reflecting three different implemented ALS-guidelines in a physician-staffed EMS.
All adult patients with non-traumatic OHCA in the EMS of Bonn from 1996 to 2011 were included. Utstein data from three 5-years time periods (1996-2001, 2001-2006, 2006-2011) representing different ALS-guideline implementations were collected. Group comparisons were made in terms of incidence, epidemiology and short-term outcome of CPR with emphasis on changes over time and factors of importance. In each group observed ROSC rate were compared to the predicted ROSC rates (the RACA score).
CPR by the ALS unit was attempted in a total of 1989 patients (735, 666, and 588 patients in the first, second and third period, respectively). Average crude incidence of CPR per 100,000 person-years decreased over time (61.3; 55.5; 49.0/100,000/years) while patients treated were significantly older (65.5 ± 16.5; 67.9 ± 15; 68.9 ± 15.7 (p<0.001)). Observed ROSC rates were higher than predicted by the RACA score in all time periods, however, admittance to ICU decreased significantly from 50% in the first five-year period to 38% last five-year period (p<0.001). From first to third period the proportion of arrests with first observed rhythm of VT/VF arrests did not change (29% vs. 27%, p=0.323) nor there were changes in bystander CPR rates (17% vs. 17%, p=0.520).
In a 15-years period and in the setting of a physician-staffed EMS the ROSC rates remain higher than predicted by the RACA score but the admittance to the ICU after OHCA declined significantly. This finding was accompanied by a decrease in CPR incidence and an increase in age of patients.
院外心脏骤停(OHCA)后的患者预后取决于心肺复苏(CPR)的实施情况,也可能受到紧急医疗服务(EMS)组织和指南实施的影响。
评估在15年期间,在由医生配备的EMS中,反映三种不同实施的高级生命支持(ALS)指南的心脏骤停后自主循环恢复(ROSC)率与心脏骤停后自主循环恢复(RACA)评分预测率的情况。
纳入1996年至2011年波恩EMS中所有非创伤性OHCA的成年患者。收集了代表不同ALS指南实施情况的三个5年时间段(1996 - 2001年、2001 - 2006年、2006 - 2011年)的Utstein数据。对CPR的发生率、流行病学和短期预后进行组间比较,重点关注随时间的变化和重要因素。将每组观察到的ROSC率与预测的ROSC率(RACA评分)进行比较。
ALS小组共对1989例患者尝试进行了CPR(第一、第二和第三时期分别为735例、666例和588例患者)。每10万人年的CPR平均粗发病率随时间下降(61.3;55.5;49.0/10万/年),而接受治疗的患者年龄显著增大(65.5±16.5;67.9±15;68.9±15.7(p<0.001))。在所有时间段,观察到的ROSC率均高于RACA评分预测值,然而,入住重症监护病房(ICU)的比例从第一个五年期的50%显著降至最后一个五年期的38%(p<0.001)。从第一时期到第三时期,首次观察到的节律为室性心动过速/心室颤动(VT/VF)的心脏骤停比例没有变化(29%对27%,p = 0.323),旁观者CPR率也没有变化(17%对17%,p = 0.520)。
在15年期间以及在由医生配备的EMS环境中,ROSC率仍高于RACA评分预测值,但OHCA后入住ICU的比例显著下降。这一发现伴随着CPR发生率的降低和患者年龄的增加。