Rito Miguel, Cabrera Rafael Adame
Serviço De Anatomia Patológica, Instituto Português De Oncologia De Lisboa Francisco Gentil, E.P.E. Lisboa, Portugal.
Diagn Cytopathol. 2015 Nov;43(11):933-6. doi: 10.1002/dc.23328. Epub 2015 Aug 25.
Chondrosarcoma is a malignant chondroid matrix-producing neoplasm which usually presents in the bones of the pelvis, followed by the proximal femur, proximal humerus, distal femur and ribs. The occurrence of this lesion in the hyoid bone is exceedingly rare, with only a few reported cases, and its diagnosis by fine-needle aspiration cytology (FNAC) in this particular location, to our knowledge, has never been addressed. Furthermore, the sampling of chondroid matrix at this site can pose a diagnostic dilemma with other lesions of the submandibular region. This report describes the clinical, radiologic and cytologic features on FNAC of a chondrosarcoma of the hyoid bone, emphasizing the diagnostic pitfalls of this entity and expanding the cytologic differential diagnosis of tumors of the submandibular region.
软骨肉瘤是一种产生软骨样基质的恶性肿瘤,通常发生于骨盆骨,其次是股骨近端、肱骨近端、股骨远端和肋骨。该病变发生于舌骨极为罕见,仅有少数病例报道,据我们所知,在这个特殊部位通过细针穿刺抽吸细胞学检查(FNAC)进行诊断的情况从未有过描述。此外,在该部位采集软骨样基质可能会与下颌下区的其他病变形成诊断难题。本报告描述了一例舌骨软骨肉瘤的临床、放射学及FNAC细胞学特征,强调了该实体的诊断陷阱,并扩展了下颌下区肿瘤的细胞学鉴别诊断。