Olasińska-Wiśniewska Anna, Grygier Marek, Lesiak Maciej, Trojnarska Olga, Araszkiewicz Aleksander, Misterski Marcin, Buczkowski Piotr, Ligowski Marcin, Jemielity Marek, Grajek Stefan
1st Department of Cardiology, Poznan University of Medical Sciences, Poznan, Poland.
Kardiol Pol. 2016;74(3):231-6. doi: 10.5603/KP.a2015.0158. Epub 2015 Aug 25.
Recently, there has been renewed interest in balloon aortic valvuloplasty (BAV).
To analyse the indications and short-term outcome of BAV since transcatheter aortic valve implantation (TAVI) was launched in our institution.
Between September 2010 and September 2014, 25 consecutive patients (19 female, 6 male) underwent BAV. The mean age was 72 ± 11.4 years, mean EuroScore II was 10.4 ± 11.7%, mean logistic EuroScore 23.5 ± 23.6%, mean Society of Thoracic Surgeons mortality risk score was 21.8 ± 13.6%. The indications for BAV were: advanced haemodynamically unstable heart failure (HF) including cardiogenic shock or pulmonary oedema (n = 7), co-morbidities requiring urgent non-cardiac surgery (n = 8), palliative treatment (n = 6), and an intention to bridge to TAVI or aortic valve replacement in patients with severe HF (n = 4).
In-hospital mortality was 20% (n = 5) and occurred in patients who underwent BAV in the setting of haemodynamically unstable HF. Other major complications included pacemaker implantation (n = 2), major vascular complications (n = 4), and cardiac tamponade (n = 1). There were no patients who required conversion to cardiac surgery. The mean peak aortic transvalvular gradient decreased from 96.9 ± 29.5 to 60.3 ± 15.5 mm Hg (p = 0.0001) after BAV. We did not observe significant aortic regurgitation.
Treatment of advanced and haemodynamically unstable aortic stenosis, bridge to non-cardiac surgery and palliative therapy are the main reasons for BAV in recent years. BAV as a bridge to TAVI or aortic valve replacement may be an option for some patients. Short-term results are good with relatively low mortality and morbidity related to the procedure. Mortality in haemodynamically unstable patients presenting with cardiogenic shock or pulmonary oedema treated with BAV is very high.
最近,人们对球囊主动脉瓣成形术(BAV)重新产生了兴趣。
分析自我院开展经导管主动脉瓣植入术(TAVI)以来BAV的适应证和短期疗效。
2010年9月至2014年9月,连续25例患者(19例女性,6例男性)接受了BAV。平均年龄为72±11.4岁,平均欧洲心脏手术风险评估系统II(EuroScore II)为10.4±11.7%,平均逻辑欧洲心脏手术风险评估系统为23.5±23.6%,平均胸外科医师协会死亡风险评分为21.8±13.6%。BAV的适应证为:晚期血流动力学不稳定的心力衰竭(HF),包括心源性休克或肺水肿(n = 7)、需要紧急非心脏手术的合并症(n = 8)、姑息治疗(n = 6),以及严重HF患者过渡到TAVI或主动脉瓣置换的意向(n = 4)。
住院死亡率为20%(n = 5),发生在血流动力学不稳定的HF患者接受BAV治疗时。其他主要并发症包括起搏器植入(n = 2)、主要血管并发症(n = 4)和心脏压塞(n = 1)。没有患者需要转为心脏手术。BAV术后主动脉跨瓣平均峰值压差从96.9±29.5降至60.3±15.5 mmHg(p = 0.0001)。我们未观察到明显的主动脉瓣反流。
治疗晚期血流动力学不稳定的主动脉瓣狭窄、过渡到非心脏手术和姑息治疗是近年来BAV的主要原因。BAV作为过渡到TAVI或主动脉瓣置换的手段可能是部分患者的一种选择。短期结果良好,与该手术相关的死亡率和发病率相对较低。血流动力学不稳定的心源性休克或肺水肿患者接受BAV治疗时死亡率非常高。