伴侣动物食物不良反应的严格评价主题（1）：排除性饮食的持续时间
Critically appraised topic on adverse food reactions of companion animals (1): duration of elimination diets.
作者信息
Olivry Thierry, Mueller Ralf S, Prélaud Pascal
机构信息
Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA.
Medizinische Kleintierklinik, Centre for Clinical Veterinary Medicine, Ludwig Maximilian University, Veterinärstrasse 13, 80539, Munich, Germany.
出版信息
BMC Vet Res. 2015 Aug 28;11:225. doi: 10.1186/s12917-015-0541-3.
BACKGROUND
Restrictive (i.e. elimination)-provocation dietary trials remain the standard of care to diagnose cutaneous adverse food reactions (CAFRs) in dogs and cats. There is currently no consensus on the duration of elimination diet trials that would permit the highest sensitivity of diagnosis of CAFR in companion animals.
RESULTS
The search for, and review and analysis of the best evidence available as of December 14, 2014 suggests that, by 5 weeks in dogs and 6 weeks in cats after starting an elimination diet, more than 80 % of patients had achieved a remission of clinical signs of CAFR. Increasing the diet trial duration to 8 weeks leads to a complete remission in more than 90 % of dogs and cats with CAFR.
CONCLUSIONS
For diagnosing CAFRs in more than 90 % of dogs and cats, elimination diet trials should last at least 8 weeks.
背景
限制性（即排除性）-激发性饮食试验仍是诊断犬猫皮肤食物不良反应（CAFR）的标准治疗方法。目前对于能使伴侣动物CAFR诊断具有最高敏感性的排除性饮食试验持续时间尚无共识。
结果
对截至2014年12月14日的现有最佳证据进行检索、回顾和分析表明，在开始排除性饮食后，犬5周、猫6周时，超过80%的患者CAFR临床症状已缓解。将饮食试验持续时间延长至8周，超过90%的患有CAFR的犬猫可实现完全缓解。
结论
为了诊断超过90%的犬猫的CAFR，排除性饮食试验应至少持续8周。
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