Wang Qi, Hu Minghua, Xu Huibi, Yang Xiangliang
No.1037 Luoyu Road, Wuhan 430074, Hubei, China.
Curr Top Med Chem. 2016;16(8):888-94. doi: 10.2174/1568026615666150827101602.
As an important hallmark in cancer progress, inflammation attracts more and more interests in recent years. Lots of evidences support the positive effect of n-3 PUFA in inflammation-associated diseases, the supplement of these fatty acids is thought to be promising in the prevention and treatment of cancers. In this review, we summarize some current knowledge of the mechanisms by which n-3 PUFA are thought to attenuate cancer associated inflammation, and we also introduce the current situation of n-3 PUFA in clinic.
作为癌症进展的一个重要标志,炎症近年来吸引了越来越多的关注。大量证据支持n-3多不饱和脂肪酸在炎症相关疾病中的积极作用,补充这些脂肪酸被认为在癌症的预防和治疗方面具有前景。在这篇综述中,我们总结了目前关于n-3多不饱和脂肪酸被认为可减轻癌症相关炎症的机制的一些知识,并且我们还介绍了n-3多不饱和脂肪酸在临床上的现状。