[Changes in fluoride levels in the blood serum and urine of children with mottled enamel].

The study comprised 46 children (25 boys and 21 girls) aged 10 to 14 years with endemic mottled enamel. From birth all children used aqueductal potable water containing supraoptimal amount of fluorine equal to 2,68 mg/ml. The control group consisted of 40 children from Lódź children care homes free from mottled enamel in whom endogenic fluoridation has been performed using Fluodar tablets according to generally accepted instructions. In both groups of children the fluorine content in the blood serum and urine has been determined. The children with mottled enamel the fluorine excretion with urine was statistically significantly higher than in the control group. Moreover, the children with mottled enamel showed higher concentration of fluorine in the urine than in the serum whereas in the control group the fluorine concentration in the urine and in the serum were almost identical.