Kalichman Seth C, Eaton Lisa, Kalichman Moira O, Cherry Chauncey
University of Connecticut, USA.
J Health Psychol. 2017 Mar;22(3):269-279. doi: 10.1177/1359105315600239. Epub 2016 Jul 10.
Medical mistrust is a significant barrier to medication adherence among African Americans living with HIV. In this study 380 African American people receiving antiretroviral therapy (ART) in a southern US city completed computerized measures at a community-based research site. Multiple mediation modeling showed that medical provider mistrust was associated with medication beliefs and ART adherence. Also, medication beliefs predicted adherence. The indirect effects of medical mistrust on adherence via medication beliefs was significant; the indirect effect was significant for medication concerns beliefs, but not medication necessity beliefs. Medication concerns beliefs therefore mediate the association between medical mistrust and ART adherence.
医疗不信任是美国南部城市感染艾滋病毒的非裔美国人坚持服药的一个重大障碍。在这项研究中，380名在美国南部城市接受抗逆转录病毒疗法（ART）的非裔美国人在一个社区研究站点完成了计算机化测量。多重中介模型显示，对医疗服务提供者的不信任与用药信念和抗逆转录病毒疗法的依从性有关。此外，用药信念可预测依从性。医疗不信任通过用药信念对依从性产生的间接影响是显著的；这种间接影响在用药担忧信念方面显著，但在用药必要性信念方面不显著。因此，用药担忧信念在医疗不信任与抗逆转录病毒疗法依从性之间起中介作用。
