Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Nat Genet. 2015 Sep;47(9):965-6. doi: 10.1038/ng.3384.
High-throughput analysis of the phenotypes of mouse genetic knockouts presents several challenges, such as systematic measurement biases that can vary with time. A report from the EUMODIC consortium presents data from 320 genetic knockouts generated using standardized phenotyping pipelines and new statistical analyses aimed at increasing reproducibility across centers.
高通量分析小鼠基因敲除的表型存在一些挑战，例如系统测量偏差，其可能随时间变化。EUMODIC 联盟的一份报告介绍了使用标准化表型分析流程和旨在提高中心间可重复性的新统计分析生成的 320 个基因敲除的数据。
