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Autophagy, a major adaptation pathway shaping cancer cell death and anticancer immunity responses following photodynamic therapy.自噬是一种主要的适应性途径，它决定了光动力疗法后癌细胞死亡和抗癌免疫反应的形成。
Photochem Photobiol Sci. 2015 Aug;14(8):1410-24. doi: 10.1039/c4pp00466c. Epub 2015 Feb 10.
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Autophagy as a pro-death pathway.自噬作为一种促死亡途径。
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Reversible effects of photodamage directed toward mitochondria.针对线粒体的光损伤的可逆效应。
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ATG7 deficiency suppresses apoptosis and cell death induced by lysosomal photodamage.ATG7 缺乏抑制溶酶体光损伤诱导的细胞凋亡和死亡。
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Cancerous cell death from sensitizer free photoactivation of singlet oxygen.敏化剂自由的单线态氧光激活诱导癌细胞死亡。
Photochem Photobiol. 2012 Jan-Feb;88(1):167-74. doi: 10.1111/j.1751-1097.2011.01028.x. Epub 2011 Nov 22.
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Atg7 deficiency increases resistance of MCF-7 human breast cancer cells to photodynamic therapy.Atg7 缺失增强 MCF-7 人乳腺癌细胞对光动力疗法的抵抗性。
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Assessing autophagy in the context of photodynamic therapy.评估光动力疗法背景下的自噬作用。
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通过光动力疗法探究自噬性死亡

Autophagic death probed by photodynamic therapy.

作者信息

Kessel David

机构信息

a Department of Pharmacology, Wayne State University School of Medicine ; Detroit , MI USA.

出版信息

Autophagy. 2015;11(10):1941-3. doi: 10.1080/15548627.2015.1078960.

DOI:10.1080/15548627.2015.1078960
PMID:26313747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4824598/
Abstract

The high degree of selectivity for photodamage to subcellular organelles can provide a means for evaluation of autophagic death pathways. While many current reports rely on ambiguous criteria, there are glimmers of unequivocal evidence.

摘要

对亚细胞器光损伤的高度选择性可为评估自噬性死亡途径提供一种手段。虽然目前许多报告依赖于模糊的标准，但也有明确证据的迹象。