Mørkenborg M-L, Frendø M, Stavngaard T, Von Buchwald C
Department of Otorhinolaryngology, Head and Neck Surgery and Audiology,Copenhagen University Hospital Rigshospitalet,Denmark.
Department of Neuroradiology,Copenhagen University Hospital Rigshospitalet,Denmark.
J Laryngol Otol. 2015 Oct;129(10):1032-5. doi: 10.1017/S0022215115001899. Epub 2015 Aug 28.
Juvenile nasopharyngeal angiofibroma is a benign, vascular tumour that primarily occurs in adolescent males. Despite its benign nature, aggressive growth patterns can cause potential life-threatening complications. Juvenile nasopharyngeal angiofibroma is normally unilateral, originating from the sphenopalatine artery, but bilateral symptoms can occur if a large tumour extends to the contralateral side of the nasopharynx. This paper presents the first reported case of true bilateral extensive juvenile nasopharyngeal angiofibroma involving clinically challenging pre-surgical planning and surgical strategy.
A 21-year-old male presented with increasing bilateral nasal obstruction and discharge. Examination revealed tumours bilaterally and imaging demonstrated non-contiguous tumours. Pre-operative angiography showed strictly ipsilateral vascular supplies requiring bilateral embolisation. Radical removal performed as one-step, computer-assisted functional endoscopic sinus surgery was performed. The follow-up period was uncomplicated.
This case illustrates the importance of suspecting bilateral juvenile nasopharyngeal angiofibroma in patients presenting with bilateral symptoms. Our management, including successful pre-operative planning, enabled one-step total removal of both tumours and rapid patient recovery.
青少年鼻咽血管纤维瘤是一种主要发生于青春期男性的良性血管肿瘤。尽管其性质为良性,但侵袭性生长模式可导致潜在的危及生命的并发症。青少年鼻咽血管纤维瘤通常为单侧,起源于蝶腭动脉,但如果大的肿瘤扩展至鼻咽对侧,则可出现双侧症状。本文报道了首例真正双侧广泛的青少年鼻咽血管纤维瘤病例,该病例涉及具有临床挑战性的术前规划和手术策略。
一名21岁男性因双侧鼻塞和流涕加重就诊。检查发现双侧肿瘤,影像学检查显示肿瘤不连续。术前血管造影显示严格的同侧血管供应,需要双侧栓塞。作为一步手术进行了根治性切除,实施了计算机辅助功能性鼻内镜鼻窦手术。随访期无并发症。
本病例说明了对于出现双侧症状的患者怀疑双侧青少年鼻咽血管纤维瘤的重要性。我们的治疗,包括成功的术前规划,实现了一次性完全切除双侧肿瘤并使患者快速康复。