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根除幽门螺杆菌以消除胃癌:日本的策略。

Helicobacter pylori Eradication to Eliminate Gastric Cancer: The Japanese Strategy.

作者信息

Asaka Masahiro, Mabe Katsuhiro, Matsushima Rumiko, Tsuda Momoko

机构信息

Cancer Preventive Medicine, Hokkaido University Graduate School of Medicine, Kita 12, Nishi 7, Kita-ku, Sapporo 060-0812, Japan.

Cancer Preventive Medicine, Hokkaido University Graduate School of Medicine, Kita 12, Nishi 7, Kita-ku, Sapporo 060-0812, Japan.

出版信息

Gastroenterol Clin North Am. 2015 Sep;44(3):639-48. doi: 10.1016/j.gtc.2015.05.010. Epub 2015 Jul 15.

Abstract

Helicobacter pylori eradication therapy for chronic gastritis achieved world-first coverage by the Japanese national health insurance scheme in 2013, making a dramatic decrease of gastric cancer-related deaths more realistic. Combining H pylori eradication therapy with endoscopic surveillance can prevent the development of gastric cancer. Even if it develops, most patients are likely to be diagnosed at an early stage, possibly resulting in fewer gastric cancer deaths. Success with the elimination of gastric cancer in Japan could lead other countries with a high incidence to consider a similar strategy, suggesting the potential for elimination of gastric cancer around the world.

摘要

2013年,日本国家医疗保险计划使慢性胃炎的幽门螺杆菌根除疗法实现了全球首次覆盖,这使得大幅降低胃癌相关死亡人数变得更加现实。将幽门螺杆菌根除疗法与内镜监测相结合可以预防胃癌的发生。即使胃癌发生了,大多数患者也可能在早期被诊断出来,这有可能减少胃癌死亡人数。日本在消除胃癌方面的成功可能会促使其他高发病率国家考虑类似的策略,这表明在全球范围内消除胃癌具有可能性。

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