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对34只疑似角膜钙质变性的犬角膜进行金刚石钻磨清创术。

Diamond burr debridement of 34 canine corneas with presumed corneal calcareous degeneration.

作者信息

Nevile Jessica C, Hurn Simon D, Turner Andrew G, Morton John

机构信息

All Animal Eye Services, 5 Andrew St Mount Waverley, Melbourne, Vic., 3149, Australia.

Jemora Pty Ltd, PO Box 2277, Geelong, Vic., 3220, Australia.

出版信息

Vet Ophthalmol. 2016 Jul;19(4):305-12. doi: 10.1111/vop.12304. Epub 2015 Aug 28.

Abstract

OBJECTIVES

To describe the signalment, presence of systemic and/or ocular comorbidities, times to detected healing and probabilities of recurrence after diamond burr debridement (DBD) of eyes with presumed corneal calcareous degeneration and secondary ulceration and/or ocular pain.

ANIMALS STUDIED

Twenty-six dogs with 42 eyes affected, 34 eyes treated with DBD.

METHODS

A case series was conducted using medical records from a private veterinary ophthalmology referral practice. Dogs were included if they had white or gray corneal opacity consistent with corneal calcareous degeneration with either erosive or superficial ulceration and/or ocular pain in at least one eye and had at least one such eye treated with DBD. DBD was performed with a battery-operated handheld motorized burr (The Alger Company, Inc. Lago Vista, TX, USA), and a bandage contact lens was placed in the majority of eyes (30/34). Eyes were considered healed when the cornea was fluorescein negative, and there were no signs of ocular pain. Patient data (signalment, recurrence) were extracted from medical records.

RESULTS

Dogs were first re-examined 7-62 days after treatment (median: 13 days). All DBD-treated eyes healed within 62 days (% healed: 100%; one-sided 97.5% CI: 90-100%, median: 14 days), 82% of eyes (28/34) were healed at first re-examination (median: 13 days after treatment), and all were healed by their second examination (median: 24 days). Of the 34 treated eyes, 11 were lost to follow up; 11 of the remaining 23 eyes recurred. Estimated 1-year recurrence probability was 58% (95% CI: 35-83%). Seven dogs had systemic disease; 7 had a history of prior ocular disease or intraocular surgery.

CONCLUSIONS

Diamond burr debridement is a safe and effective treatment for rapid resolution of superficial corneal ulceration and ocular pain secondary to presumed corneal calcareous degeneration in dogs.

摘要

目的

描述疑似角膜钙质沉着变性继发溃疡和/或眼痛的犬眼在进行钻石钻磨清创术(DBD)后的特征、全身和/或眼部合并症情况、检测到愈合的时间以及复发概率。

研究动物

26只犬的42只眼受累,34只眼接受了DBD治疗。

方法

采用一家私人兽医眼科转诊机构的病历进行病例系列研究。纳入标准为至少一只眼有与角膜钙质沉着变性相符的白色或灰色角膜混浊,并伴有糜烂性或浅表性溃疡和/或眼痛,且至少有一只这样的眼接受了DBD治疗。使用电池驱动的手持式电动钻磨器(美国得克萨斯州拉戈维斯塔市阿尔杰公司)进行DBD,大多数眼睛(30/34)放置了绷带式隐形眼镜。当角膜荧光素染色阴性且无眼痛迹象时,眼睛被视为愈合。从病历中提取患者数据(特征、复发情况)。

结果

治疗后7 - 62天(中位数:13天)首次对犬进行复查。所有接受DBD治疗的眼睛均在62天内愈合(愈合率:100%;单侧97.5%可信区间:90 - 100%,中位数:14天),82%的眼睛(28/34)在首次复查时愈合(治疗后中位数:13天),所有眼睛在第二次复查时均愈合(中位数:24天)。在34只接受治疗的眼睛中,11只失访;其余23只眼睛中有11只复发。估计1年复发概率为58%(95%可信区间:35 - 83%)。7只犬有全身疾病;7只犬有既往眼部疾病或眼内手术史。

结论

钻石钻磨清创术是一种安全有效的治疗方法,可快速缓解犬疑似角膜钙质沉着变性继发的浅表性角膜溃疡和眼痛。

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