1970 - 1986年匈牙利的联体双胞胎

Conjoined twins in Hungary, 1970-1986.

作者信息

Métneki J, Czeizel A

机构信息

Department of Human Genetics and Teratology, WHO Collaborating Centre for the Community Control of Hereditary Diseases, National Institute of Hygiene, Budapest, Hungary.

出版信息

Acta Genet Med Gemellol (Roma). 1989;38(3-4):285-99. doi: 10.1017/s0001566000002695.

DOI:10.1017/s0001566000002695

PMID:2631499

Abstract

The total prevalence of conjoined twins (birth + prenatally diagnosed) was 1:68,000 in the study of 1970-1986. Symmetrical cases (the so-called siamese twins) have an obvious predominance (92.3%). Associated major malformations occurred in 80% of conjoined twins and more than 1/5 were discordant. The surviving time of liveborn conjoined twin sets was not more than two days except in two surgically successfully separated pairs. The family study did not indicate a higher recurrence risk. The case group was compared to two control groups and it appeared that the periconceptional use of oral contraception and ovulation induction were mentioned more frequently in pregnancies resulting in conjoined twins.

摘要

在1970年至1986年的研究中，联体双胎（出生时 + 产前诊断）的总患病率为1:68,000。对称型病例（即所谓的暹罗双胎）明显占优势（92.3%）。80%的联体双胎伴有严重畸形，超过五分之一的联体双胎不一致。除了两对手术分离成功的活产联体双胎外，其他活产联体双胎的存活时间不超过两天。家族研究未显示出更高的复发风险。将病例组与两个对照组进行比较，结果显示，在导致联体双胎的妊娠中，受孕前使用口服避孕药和促排卵的情况被提及得更为频繁。