Giżewska Agnieszka, Witkowska-Patena Ewa, Stembrowicz-Nowakowska Zofia, Mazurek Andrzej, Osiecki Sebastian, Kowalski Łukasz, Dziuk Mirosław, Slomka Marta
Department of Nuclear Medicine, Military Institute of Medicine, Warsaw, Poland.
Nucl Med Rev Cent East Eur. 2015;18(2):89-91. doi: 10.5603/NMR.2015.0021.
The aim of this study was to assess the prevalence of long bone metastases in renal cancer patients and to evaluate their utility as predictors of survival in this group.
This retrospective study included 20 patients with metastatic renal cancer and bone metastases. The patients were referred for regular bone scintigraphy in order to assess disease spread in the skeleton. The patients were divided into two groups: those with 1) metastases in the skeleton (including long bones) and those with 2) metastases in the axial skeleton only.
Bone scintigraphy imaging was performed regularly up to 81 months from the first positive bone scan. During that time 11 deaths (8 among patients with long bone lesions) were recorded. Kaplan-Meyer curves showed that patients with long bone metastases tend to have lower survival probability in comparison to the ones with metastases in other bones.
Bone metastases localization seems to influence survival in patients with renal cancer. Long bone-involving spread of the disease is associated with worse survival probability than the spread to the other bones.
本研究旨在评估肾癌患者长骨转移的发生率，并评估其作为该组患者生存预测指标的效用。
这项回顾性研究纳入了20例发生转移性肾癌且有骨转移的患者。患者接受定期骨闪烁扫描以评估疾病在骨骼中的扩散情况。患者被分为两组：1）骨骼（包括长骨）有转移的患者和2）仅轴向骨骼有转移的患者。
从首次骨扫描呈阳性开始，定期进行骨闪烁扫描成像长达81个月。在此期间，记录到11例死亡（长骨病变患者中有8例）。Kaplan - Meyer曲线显示，与其他骨骼有转移的患者相比，长骨有转移的患者生存概率往往较低。
骨转移的部位似乎会影响肾癌患者的生存。疾病累及长骨的扩散与扩散至其他骨骼相比，生存概率更差。
