Alves Victor M, Vieira Tiago S, Amorim Nelson S, Oliveira Ana, Rodrigues André, Pereira Jorge G
Department of Nuclear Medicine, São João Hospital Center, Porto, Portugal.
Nucl Med Rev Cent East Eur. 2015;18(2):97-101. doi: 10.5603/NMR.2015.0023.
The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single photon emission computed tomography/computed tomography (SPECT/CT) and histological examination. Together these findings gave the definitive diagnosis. This is the first case ever published with 99mTc(V)-DMSA SPECT-CT. Advances on the knowledge of disease suggests that this imaging procedure could have utility in diagnosis and evaluation of the disease activity and therapy response.
戈勒姆-斯托特病是一种非常罕见的病症，其特征为淋巴管增生和大量骨质吸收。我们报告一例48岁男性患者，其左股骨头、颈部以及同侧髋臼出现骨质溶解。除了形态学成像外，他还接受了骨闪烁显像、锝-99m-V-二巯基丁二酸[99mTc(V)-DMSA]单光子发射计算机断层扫描/计算机断层扫描（SPECT/CT）以及组织学检查。这些检查结果共同得出了明确诊断。这是首例发表的使用99mTc(V)-DMSA SPECT-CT的病例。对该疾病认识的进展表明，这种成像方法在疾病诊断、评估疾病活动度及治疗反应方面可能具有实用价值。
