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[旋毛虫T3所致肌炎的临床生物学特征,特别涉及一项风湿病学研究]

[Clinico-biological aspects of myositis due to Trichinella T3 with special regard to a rheumatologic study].

作者信息

Ferraccioli G F, Mercadanti M, Salaffi F, Melissari M, Marbini A, Pozio E

出版信息

Ann Ist Super Sanita. 1989;25(4):641-7.

PMID:2631629
Abstract

One hundred and fifty patients living in Salsomaggiore Terme developed signs and symptoms of trichinellosis after eating infected horse meat. The etiological agent was identified as Trichinella T3. This large outbreak gave us the opportunity of studying the rheumatic manifestations during this kind of parasitic disease. Myositis was observed in 62% of the entire series whereas arthralgias were recorded in only 20% of the patients. The muscle pain was described in several ways, but in the majority it appeared during isokinetic movements. The scapular girdle was involved much more than the pelvic girdle. Arthralgias correlated with the degree of myositis, thus allowing us to conclude that the involvement of the muscle groups proximal to the joint clearly determined a painful sensation in the joint itself. Our histopathologic data suggest that the eosinophils may play an important role in the myositis process.

摘要

150名居住在萨尔索马焦雷泰尔梅的患者在食用受感染的马肉后出现了旋毛虫病的体征和症状。病原体被鉴定为旋毛虫T3型。这次大规模疫情使我们有机会研究这种寄生虫病期间的风湿性表现。在整个病例系列中,62%的患者观察到肌炎,而只有20%的患者记录到关节痛。肌肉疼痛有多种描述方式,但大多数在等速运动时出现。肩胛带比骨盆带受累更多。关节痛与肌炎程度相关,因此我们可以得出结论,关节近端肌肉群的受累明显导致关节本身产生疼痛感。我们的组织病理学数据表明,嗜酸性粒细胞可能在肌炎过程中起重要作用。

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