Reuter B M, Linke D B, Kurthen M
Arch Psychol (Frankf). 1989;141(3):155-73.
P300 is the most investigated component of the event-related potentials. Being the correlate of an active target discrimination and decision making process it is seen as related to cognition. Such elementary cognitive processes--as expressed in P300--can happen even in states of coma. In four of 35 comatose patients with diffuse head injury we were able to measure the P3-wave showing frontal and parietal components. Accordingly some unawakable patients can still recognize differences in pitch. The structure of components and their psychophysiological meaning are discussed.
P300是事件相关电位中研究最多的成分。作为主动目标辨别和决策过程的相关指标，它被视为与认知相关。这种在P300中表现出来的基本认知过程，甚至在昏迷状态下也可能发生。在35例弥漫性颅脑损伤的昏迷患者中，有4例我们能够测量到显示额部和顶叶成分的P3波。因此，一些无法唤醒的患者仍然能够识别音高差异。文中讨论了这些成分的结构及其心理生理学意义。
