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三级护理头痛中心就诊患者的阿片类药物和巴比妥类药物处方调查。

Survey of Opioid and Barbiturate Prescriptions in Patients Attending a Tertiary Care Headache Center.

作者信息

Minen Mia T, Lindberg Kate, Wells Rebecca E, Suzuki Joji, Grudzen Corita, Balcer Laura, Loder Elizabeth

机构信息

Department of Neurology, NYU Langone Medical Center.

Barnard College, Columbia University, NY, USA.

出版信息

Headache. 2015 Oct;55(9):1183-91. doi: 10.1111/head.12645. Epub 2015 Aug 28.

Abstract

OBJECTIVE

To educate physicians about appropriate acute migraine treatment guidelines by determining (1) where headache patients were first prescribed opioids and barbiturates, and (2) the characteristics of the patient population who had been prescribed opioids and barbiturates.

BACKGROUND

Several specialty societies issued recommendations that caution against the indiscriminate use of opioids or barbiturate containing medications for the treatment of migraine. These medications are still being prescribed in various medical settings and could put headache specialists in a difficult position when patients request these agents.

METHODS

Patients presenting to a headache center comprised of eight physicians were asked to complete a survey that assessed headache types, comorbid conditions, and whether they had ever been prescribed opioids or barbiturates. If they responded affirmatively to the latter question, they were asked about the prescribing doctor, medication effectiveness, and whether they were currently on the medication. Data collection took place over a one month period.

RESULTS

Two hundred forty-four patients were given the survey and 218 of these patients completed it. The predominant diagnosis was migraine (83.9%). More than half of the patients reported having been prescribed an opioid (54.8%) or a barbiturate (56.7%). About one fifth were on opioids (19.4%) or barbiturates (20.7%) at the time of completing the survey. Most patients reported being on opioids for more than 2 years (24.6%) or less than one week (32.1%). The reasons most frequently cited for stopping opioids were that the medications did not help (30.9%) or that they saw a new doctor who would not prescribe them (29.4%). Among patients who had previously been on barbiturates, 32.2% had been on these for over 2 years. Most patients (61.8%) stopped barbiturates because they did not find the medication helpful, while 17.6% said they saw a new doctor who would not prescribe them. The physician specialty most frequently cited as being the first prescriber for opioids was emergency medicine (20.2%) with family doctors and general neurologists the next groups at 17.7% each. General neurologists were the most frequent (37.8%) first prescribers of barbiturates.

CONCLUSIONS

Approximately 20% of patients presenting to a headache center reported current use of opioids and/or barbiturates. ED physicians were reported to be the most frequent first prescribers of opioids and general neurologists were the most frequent first prescribers of barbiturates. Taken as a whole, these data provide a useful snapshot of the wide variety of physician specialties that might benefit from additional education on the appropriate use of opioids and barbiturate-containing medications in patients with headaches.

摘要

目的

通过确定(1)头痛患者首次被开具阿片类药物和巴比妥类药物的地点,以及(2)被开具阿片类药物和巴比妥类药物的患者群体特征,对医生进行适当的急性偏头痛治疗指南教育。

背景

几个专业学会发布了相关建议,告诫不要不加区分地使用阿片类药物或含巴比妥类药物的制剂来治疗偏头痛。这些药物仍在各种医疗环境中被开具处方,当患者要求使用这些药物时,可能会使头痛专科医生陷入困境。

方法

要求到由八位医生组成的头痛中心就诊的患者完成一项调查,该调查评估头痛类型、合并症,以及他们是否曾被开具过阿片类药物或巴比妥类药物。如果他们对后一个问题回答是肯定的,会被问及开处方的医生、药物疗效,以及他们目前是否正在服用该药物。数据收集在一个月的时间内进行。

结果

244名患者接受了调查,其中218名患者完成了调查。主要诊断为偏头痛(83.9%)。超过一半的患者报告曾被开具过阿片类药物(54.8%)或巴比妥类药物(56.7%)。在完成调查时,约五分之一的患者正在服用阿片类药物(19.4%)或巴比妥类药物(20.7%)。大多数患者报告服用阿片类药物超过2年(24.6%)或少于一周(32.1%)。最常被提及的停用阿片类药物的原因是药物无效(30.9%)或他们看了新医生,新医生不开具这些药物(29.4%)。在曾服用过巴比妥类药物的患者中,32.2%服用这些药物超过2年。大多数患者(61.8%)停用巴比妥类药物是因为他们觉得药物无效,而17.6%的患者表示他们看了新医生,新医生不开具这些药物。最常被提及作为阿片类药物首位开处方医生的内科专业是急诊医学(20.2%),家庭医生和普通神经科医生并列其次,各占17.7%。普通神经科医生是巴比妥类药物最常出现的(37.8%)首位开处方医生。

结论

到头痛中心就诊的患者中,约20%报告目前正在使用阿片类药物和/或巴比妥类药物。据报告,急诊内科医生是阿片类药物最常出现的首位开处方医生,普通神经科医生是巴比妥类药物最常出现的首位开处方医生。总体而言,这些数据提供了一个有用的概况,表明各类内科专业医生可能都能从关于头痛患者适当使用阿片类药物和含巴比妥类药物的额外教育中受益。

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