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[人类出生后发育各阶段冠状动脉神经肌肉关系系统的测定]

[Determination in the system of the neuromuscular relations of the coronary arteries at stages in human postnatal development].

作者信息

Stovichek Iu G

出版信息

Arkh Anat Gistol Embriol. 1989 Dec;97(12):37-40.

PMID:2631650
Abstract

By means of micromorphometric method in transversal sections of electively stained right and left coronary arteries the data, characterizing the area of the middle and external sheaths, amount of myelin fibers in nerves, accompanying the artery have been obtained in men of 8 age groups (from birth up to old age), who died from causes not connected with the cardiovascular pathology. The summary amount of all classes of myelin fibers increases synchronously with an increase of the muscle sheath area from newborn up to 35-45 years of age. After this age the amount of the myelin fibers decreases together with decreasing area of the middle sheath. Minimal values of these indices are observed in the old age (85-90 years). The external sheath area increases permanently from birth up to the old age. The correlative analysis reveals a positive and significant connection of various degree between the myelin fibers number and value of the middle arterial sheath in persons of juvenile, mature and elderly age: amount of the muscular layer is adequate to the myelin fibers amount. In other age groups the correlative connections are either small, or not significant. Alternative, corresponding to each age quantitative gradations of the nervous connections are determined by means of the peripheral substrate. Its role in the vessels investigated is performed, to a definite degree, by the muscle sheath.

摘要

通过显微形态测量法,对经选择性染色的左右冠状动脉横切面进行研究,获取了8个年龄组(从出生到老年)男性的数据,这些男性死于与心血管病理无关的原因,数据包括中膜和外膜的面积、动脉伴行神经中髓鞘纤维的数量。从新生儿到35 - 45岁,所有类型髓鞘纤维的总量随着肌层面积的增加而同步增加。这个年龄之后,髓鞘纤维的数量随着中膜面积的减小而减少。这些指标的最小值出现在老年(85 - 90岁)。外膜面积从出生到老年持续增加。相关分析显示,在青少年、成年人和老年人中,髓鞘纤维数量与动脉中膜值之间存在不同程度的正相关且显著相关:肌层的量与髓鞘纤维的量相适应。在其他年龄组中,相关联系要么较小,要么不显著。通过外周基质确定了与每个年龄相对应的神经联系的定量分级。在一定程度上,肌层在被研究的血管中发挥了其作用。

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