Yamada Rika, Hirose Fumitaka, Matsuki Takaaki, Kameda Takanori, Kurimoto Yasuo
Department of Ophthalmology, Kobe City Medical Center General Hospital, Chuo-ku, Kobe, Hyogo, Japan.
J Glaucoma. 2016 Jun;25(6):482-6. doi: 10.1097/IJG.0000000000000310.
To investigate the relationship between angle configuration and diagnostic provocation tests such as the mydriatic provocative test (MPT) and the dark room prone provocative test (DRPPT).
Seventy eyes of 70 consecutive patients with primary angle closure suspect, primary angle closure, or primary angle closure glaucoma were included. The anterior chamber depth, angle opening distance 500, trabecular-iris space area 500, and iris thickness (IT) were quantitatively determined by anterior segment optical coherence tomography, and the MPT and DRPPT were used to investigate intraocular pressure variations.
Seven eyes were positive and 3 eyes were suspected positive, using the MPT, whereas 10 eyes were positive and 7 eyes were suspected positive using the DRPPT. The anterior chamber depth and angle opening distance 500 of the positive and suspected positive groups (positive group), using the MPT, were significantly less than those of the negative group (P=0.013, P=0.013, respectively). IT of the positive group, using the MPT, was significantly greater than the negative group, using the same test (P=0.003). The trabecular-iris space area 500 of the positive group was significantly less than the negative group, using both the MPT (P<0.001) and the DRPPT (P=0.004).
Eyes from the positive group, using the MPT, contained a shallower anterior chamber, narrower angle, and greater IT than those from the negative group. These results suggested that the MPT results better correlated with the anterior chamber angle configuration in eyes with primary angle closure, than the results using the DRPPT.
研究角度结构与散瞳激发试验（MPT）和暗室俯卧激发试验（DRPPT）等诊断性激发试验之间的关系。
纳入70例连续的原发性闭角型青光眼可疑患者、原发性闭角型青光眼患者或原发性闭角型青光眼患者的70只眼。通过眼前节光学相干断层扫描定量测定前房深度、500角开放距离、小梁-虹膜间隙面积500和虹膜厚度（IT），并使用MPT和DRPPT研究眼压变化。
使用MPT时，7只眼为阳性，3只眼疑似阳性；而使用DRPPT时，10只眼为阳性，7只眼疑似阳性。使用MPT时，阳性和疑似阳性组（阳性组）的前房深度和500角开放距离明显小于阴性组（分别为P = 0.013，P = 0.013）。使用MPT时，阳性组的IT明显大于阴性组（P = 0.003）。使用MPT（P < 0.001）和DRPPT（P = 0.004）时，阳性组的小梁-虹膜间隙面积500均明显小于阴性组。
使用MPT时，阳性组的眼睛比阴性组的眼睛前房更浅、房角更窄且IT更大。这些结果表明，与使用DRPPT的结果相比，MPT结果与原发性闭角型青光眼患者的前房角结构相关性更好。
