Granic Miroslav, Stefanovic-Radovic Magdalena, Zdravkovic Darko, Ivanovic Nebojsa, Nikolic Dejan, Radovanovic Dragan, Stojiljkovic Miodrag
Department of Surgical Oncology, University Medical Center "Bezanijska kosa", Belgrade, Serbia, Faculty of Medicine, University of Belgrade, Serbia.
Department of Radiology, University Medical Center "Bezanijska kosa", Serbia.
Arch Iran Med. 2015 Sep;18(9):608-12.
The most common location of the leiomyoma is uterus, small bowel and the esophagus, however they can occur in any organ. Intraparenchimal leiomyomas of the breast are very rare and only 30 cases were reported in the literature. These histologically benign tumors, may mimic malignancies and therefore may present a diagnostic challenge. Here, we present two new cases. The first case was a 50-year-old woman presented with a 4 cm firm mass in her right breast with discrete localized skin thickening/retraction. The second case was a 35-year-old woman presented with a painless palpable lump in the lower outer quadrant of her right breast. Physical examination, mammography and ultrasound as well as surgical excision were performed in both cases. According to histologic examination and immunohistochemical analysis, a diagnosis of smooth muscle tumor of the breast was made. These tumors clinically and radiologically mimic other breast lesions. Neither imaging studies nor palpation allow distinction between benign and malignant tumors.
平滑肌瘤最常见的发生部位是子宫、小肠和食管，不过它们可出现在任何器官。乳腺实质内平滑肌瘤非常罕见，文献中仅报道过30例。这些组织学上为良性的肿瘤可能类似恶性肿瘤，因此可能带来诊断挑战。在此，我们报告两例新病例。第一例是一名50岁女性，其右乳有一个4厘米的实性肿块，伴有局限性皮肤增厚/回缩。第二例是一名35岁女性，其右乳外下象限有一个可触及的无痛肿块。两例均进行了体格检查、乳腺X线摄影、超声检查以及手术切除。根据组织学检查和免疫组化分析，诊断为乳腺平滑肌瘤。这些肿瘤在临床和影像学上类似其他乳腺病变。影像学检查和触诊均无法区分良性和恶性肿瘤。
