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Review of health risks of low testosterone and testosterone administration.低睾酮水平及睾酮给药的健康风险综述。
World J Clin Cases. 2015 Apr 16;3(4):338-44. doi: 10.12998/wjcc.v3.i4.338.
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Cardiovascular risk associated with testosterone-boosting medications: a systematic review and meta-analysis.与促睾酮药物相关的心血管风险:一项系统评价与荟萃分析
Expert Opin Drug Saf. 2014 Oct;13(10):1327-51. doi: 10.1517/14740338.2014.950653. Epub 2014 Aug 19.
3
Reoperation after combat-related major lower extremity amputations.与战斗相关的下肢大截肢术后再次手术
J Orthop Trauma. 2014 Apr;28(4):232-7. doi: 10.1097/BOT.0b013e3182a53130.
4
Managing endocrine dysfunction following blast injury to the male external genitalia.男性外生殖器爆炸伤后内分泌功能障碍的管理
J R Army Med Corps. 2013 Mar;159 Suppl 1:i45-8. doi: 10.1136/jramc-2013-000022.
5
Immediate surgical management of combat-related injury to the external genitalia.
J R Army Med Corps. 2013 Mar;159 Suppl 1:i18-20. doi: 10.1136/jramc-2013-000023.
6
Testosterone therapy and cardiovascular events among men: a systematic review and meta-analysis of placebo-controlled randomized trials.睾酮治疗与男性心血管事件:安慰剂对照随机试验的系统评价和荟萃分析。
BMC Med. 2013 Apr 18;11:108. doi: 10.1186/1741-7015-11-108.
7
Dog bite injuries of genitalia in male infant and children.男童生殖器的犬咬伤
Urol Ann. 2011 Sep;3(3):167-9. doi: 10.4103/0974-7796.84949.
8
Testosterone therapy in men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline.男性雄激素缺乏综合征的睾酮治疗:内分泌学会临床实践指南。
J Clin Endocrinol Metab. 2010 Jun;95(6):2536-59. doi: 10.1210/jc.2009-2354.
9
Fatal Actinomucor elegans var. kuwaitiensis infection following combat trauma.创伤后继发致命的科威特射囊组织胞浆菌感染
J Clin Microbiol. 2009 Oct;47(10):3394-9. doi: 10.1128/JCM.00797-09. Epub 2009 Aug 12.
10
Prevalence of symptomatic androgen deficiency in men.男性有症状性雄激素缺乏的患病率。
J Clin Endocrinol Metab. 2007 Nov;92(11):4241-7. doi: 10.1210/jc.2007-1245. Epub 2007 Aug 14.

战斗损伤后的创伤性男性更年期

Traumatic andropause after combat injury.

作者信息

Jones Gareth Huw, Kirkman-Brown Jackson, Sharma Davendra Murray, Bowley Douglas

机构信息

Department of Otolaryngology Head and Neck, Fairfield General Hospital, Bury, UK.

Centre for Human Reproductive Science (ChRS), Birmingham, UK.

出版信息

BMJ Case Rep. 2015 Aug 28;2015:bcr2014207924. doi: 10.1136/bcr-2014-207924.

DOI:10.1136/bcr-2014-207924
PMID:26318170
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4693129/
Abstract

In association with lower extremity amputation, complex genitourinary injuries have emerged as a specific challenge in modern military trauma surgery. Testicular injury or loss has profound implications for the recovering serviceman, in terms of hormone production and future fertility. The initial focus of treatment for patients with traumatic testicular loss is haemostasis, resuscitation and management of concurrent life-threatening injuries. Multiple reoperations are commonly required to control infection in combat wounds; in a review of 300 major lower extremity amputations, 53% of limbs required revisional surgery, with infection the commonest indication. Atypical infections, such as invasive fungal organisms, can also complicate military wounding. We report the case of a severely wounded serviceman with complete traumatic andropause, whose symptomatic temperature swings were initially mistaken for signs of occult sepsis.

摘要

与下肢截肢相关的复杂泌尿生殖系统损伤已成为现代军事创伤外科中的一项特殊挑战。睾丸损伤或缺失对正在康复的军人在激素分泌和未来生育能力方面有着深远影响。创伤性睾丸缺失患者的初始治疗重点是止血、复苏以及对同时存在的危及生命的损伤进行处理。通常需要多次再次手术来控制战伤感染;在对300例主要下肢截肢病例的回顾中,53%的肢体需要进行翻修手术,其中感染是最常见的指征。非典型感染,如侵袭性真菌生物,也会使战伤情况复杂化。我们报告了一名严重受伤军人出现完全性创伤性更年期的病例,其有症状的体温波动最初被误诊为隐匿性脓毒症的迹象。