McAlpine J M, Scott R, Scuffham P A, Perkins A V, Vanderlelie J J
School of Medical Science, Menzies Health Institute Queensland, Griffith University Gold Coast Campus, Southport, QLD, Australia; Department of Women's and Newborn Health, Gold Coast University Hospital, Southport, QLD, Australia.
School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast Campus, Southport, QLD, Australia.
Women Birth. 2016 Feb;29(1):41-6. doi: 10.1016/j.wombi.2015.07.185. Epub 2015 Aug 28.
Widespread use of maternal micronutrient supplements have been correlated to gestational length and outcome in women predisposed to pre-eclampsia and preterm birth. However, research is yet to be conducted examining the influence of micronutrient supplements on outcomes at term in uncomplicated pregnancies.
To analyse the relationship between third trimester micronutrient supplementation and gestation length at birth, demographics and maternal birthing outcomes in well women at term in a South East Queensland representative population.
This research retrospectively analysed existing data pertaining to 427 uncomplicated, pregnancies birthing at the Gold Coast and Logan Hospitals using information gathered through the Environments for Healthy Living Study and Queensland perinatal data collection. Data were analysed using SPSS v20 by Chi square, ANOVA and regression analysis.
Women in the third trimester taking individual zinc, folic acid or iron supplements in combination with a multivitamin were twice as likely to birth beyond 41 completed weeks (AOR 2.054, 95% CI 1.310-7.383, p=0.038) then those who did not take any supplement when controlled for established confounders. Non supplement users were found to experience a lower rate of post dates labour and requirements for induction (AOR 0.483, 95% CI 0.278-0.840, p=0.01).
Length of gestation demonstrates significant associations with micronutrient supplementation practices. Well women consuming third trimester individual micronutrient supplements in addition to multivitamins experienced a longer gestation at term compared to women taking no micronutrients, increasing their risk for postdates induction of labour.
孕妇广泛使用微量营养素补充剂与子痫前期和早产倾向女性的孕周及结局相关。然而,尚未开展研究探讨微量营养素补充剂对无并发症妊娠足月结局的影响。
分析昆士兰东南部代表性人群中,足月健康女性孕晚期补充微量营养素与出生时孕周、人口统计学特征及孕产妇分娩结局之间的关系。
本研究回顾性分析了通过健康生活环境研究和昆士兰围产期数据收集所获得的、与在黄金海岸和洛根医院分娩的427例无并发症妊娠相关的现有数据。使用SPSS v20通过卡方检验、方差分析和回归分析对数据进行分析。
孕晚期服用锌、叶酸或铁单一补充剂并同时服用多种维生素的女性,在控制既定混杂因素后,其孕周超过41足周的可能性是未服用任何补充剂女性的两倍(调整后比值比2.054,95%置信区间1.310 - 7.383,p = 0.038)。未服用补充剂的女性过期产和引产需求发生率较低(调整后比值比0.483,95%置信区间0.278 - 0.840,p = 0.01)。
孕周与微量营养素补充实践存在显著关联。与未服用微量营养素的女性相比,孕晚期除服用多种维生素外还服用单一微量营养素补充剂的健康女性足月妊娠时间更长,增加了过期引产的风险。