School of Nursing and Midwifery, Griffith University Logan Campus, Brisbane, Queensland, Australia.
School of Medical Science, Menzies Health Institute Queensland, Griffith University Gold Coast Campus, Southport, Queensland, Australia.
Aust N Z J Obstet Gynaecol. 2020 Aug;60(4):561-567. doi: 10.1111/ajo.13109. Epub 2020 Jan 5.
Multiple micronutrient supplement use in the Australian pregnant population is rising, despite little evidence of benefit in low-risk women. While some supplement recommendations are grounded in high-quality evidence, others warrant further investigation. This highlights a research gap regarding appropriate use of supplements during pregnancy in the Australian population.
To describe micronutrient supplement use during pregnancy in the context of current evidence and national recommendations in a population of south-east Queensland women.
A cross-sectional observational design was used to examine data gathered from pregnant women aged 16-44 years residing in south-east Queensland, Australia. Women were recruited to the study between 23 May 2016 and 30 September 2017.
Pregnancy multivitamin use was declared by 42% of the cohort, with 26.8% declaring multivitamins in combination with individual micronutrients and 9.8% declaring specific micronutrient supplement use. Nulliparous women were more likely to declare use of supplements than their multiparous peers (adjusted odds ratio (aOR) 1.938, 95% CI 1.053-3.571, P = 0.034); smoking (aOR 2.717, 95% CI 1.011-7.302, P = 0.047) and low socio-economic status were associated with no supplement use (aOR 2.451, 95% CI 1.010-5.949, P = 0.048).
Current recommendations regarding micronutrient supplements throughout pregnancy are based on varying degrees of evidence, resulting in supplement advice of poor cohesion and consistency. Adherence to micronutrient supplement recommendations in the peri-conception period in this population was poor; second and third trimester supplement use was high. Contemporary empirical research is required to determine what constitutes appropriate supplementation in high-income regions and the populations they will benefit most.
尽管在低风险女性中补充多种微量营养素的益处证据有限，但澳大利亚孕妇人群中补充多种微量营养素的现象日益增多。虽然一些补充建议基于高质量的证据，但其他建议则需要进一步研究。这突显了澳大利亚人群中有关妊娠期间适当使用补充剂的研究空白。
在昆士兰州东南部妇女当前的证据和国家建议背景下，描述妊娠期间微量营养素补充剂的使用情况。
采用横断面观察设计，研究了澳大利亚昆士兰州东南部年龄在 16-44 岁之间的孕妇的数据。2016 年 5 月 23 日至 2017 年 9 月 30 日期间招募了这些女性参加研究。
42%的研究对象报告了妊娠复合维生素的使用，其中 26.8%的研究对象报告了复合维生素与个别微量营养素联合使用，9.8%的研究对象报告了特定微量营养素补充剂的使用。与多产妇相比，初产妇更有可能报告使用补充剂（调整后的优势比 (aOR) 1.938，95%置信区间 (CI) 1.053-3.571，P=0.034）；吸烟（aOR 2.717，95%CI 1.011-7.302，P=0.047）和低社会经济地位与不使用补充剂相关（aOR 2.451，95%CI 1.010-5.949，P=0.048）。
目前关于整个孕期补充微量营养素的建议是基于不同程度的证据，导致补充建议缺乏凝聚力和一致性。该人群在围孕期内对微量营养素补充建议的依从性较差；第二和第三孕期的补充剂使用率较高。需要进行当代实证研究，以确定在高收入地区和最受益的人群中，适当的补充剂是什么。
