Chikvashvili R I, Monaselidze D R, Makhonova L A, Balakirev S A
Biofizika. 1989 Nov-Dec;34(6):1055-9.
The age dependence of haemoglobin denaturation temperature in the composition of erythrocytes is established. Children have a much more expressed correlation of this temperature depending on the type and stage of disease than the adult. It is found that children ill with leukemia have haemoglobin, the value of heat denaturation of which is decreased about 15-25% in relation to the norm. Tests are created. They allow to reveal leukemia by heat parameters of haemoglobin denaturation of the whole blood.
确定了红细胞成分中血红蛋白变性温度的年龄依赖性。与成年人相比，儿童的这种温度与疾病类型和阶段的相关性更为明显。发现患白血病的儿童的血红蛋白，其热变性值相对于正常情况降低了约15 - 25%。创建了相关测试。这些测试能够通过全血血红蛋白变性的热参数来揭示白血病。
