Shinn Justin, Paauw Douglas S
Department of Internal Medicine, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98115, USA.
Division of General Internal Medicine, Department of Medicine, University of Washington School of Medicine, 1959 NE Pacific Street, Seattle, WA 98195, USA.
Med Clin North Am. 2015 Sep;99(5):1123-48. doi: 10.1016/j.mcna.2015.05.008. Epub 2015 Jul 2.
Sarcoidosis is an idiopathic inflammatory disorder characterized by noncaseating granulomas, which can affect any organ system. The lungs are most commonly affected but extrapulmonary sites may cause the initial and/or sole symptoms. In this review, the disease manifestations and treatment are described, with particular emphasis on the management of each affected organ system. Diagnosis and management can be difficult and greatly affect quality of life, but despite these challenges, it is possible to successfully manage patients with sarcoidosis in the primary care setting.
结节病是一种特发性炎症性疾病，其特征为非干酪样肉芽肿，可累及任何器官系统。肺部最常受累，但肺外部位可能引起初始症状和/或唯一症状。在本综述中，描述了该疾病的表现和治疗方法，特别强调了对每个受累器官系统的管理。诊断和管理可能具有挑战性，并且会极大地影响生活质量，但尽管存在这些挑战，在初级保健环境中成功管理结节病患者是有可能的。
