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用于经导管主动脉瓣置换术候选者主动脉根部评估的新型超声心动图三维自动化软件的准确性和可重复性

Accuracy and reproducibility of novel echocardiographic three-dimensional automated software for the assessment of the aortic root in candidates for thanscatheter aortic valve replacement.

作者信息

García-Martín Ana, Lázaro-Rivera Carla, Fernández-Golfín Covadonga, Salido-Tahoces Luisa, Moya-Mur Jose-Luis, Jiménez-Nacher Jose-Julio, Casas-Rojo Eduardo, Aquila Iolanda, González-Gómez Ariana, Hernández-Antolín Rosana, Zamorano José Luis

机构信息

Department of Cardiology, Ramón y Cajal University Hospital, Ctra. Colmenar, km 9,100, Madrid 28034, Spain

Department of Cardiology, Ramón y Cajal University Hospital, Ctra. Colmenar, km 9,100, Madrid 28034, Spain.

出版信息

Eur Heart J Cardiovasc Imaging. 2016 Jul;17(7):772-8. doi: 10.1093/ehjci/jev204. Epub 2015 Aug 27.

DOI:10.1093/ehjci/jev204
PMID:26320167
Abstract

AIMS

A specialized three-dimensional transoesophageal echocardiography (3D-TOE) reconstruction tool has recently been introduced; the system automatically configures a geometric model of the aortic root from the images obtained by 3D-TOE and performs quantitative analysis of these structures. The aim of this study was to compare the measurements of the aortic annulus (AA) obtained by the new model to that obtained by 3D-TOE and multidetector computed tomography (MDCT) in candidates to transcatheter aortic valve implantation (TAVI) and to assess the reproducibility of this new method.

METHODS AND RESULTS

We included 31 patients who underwent TAVI. The AA diameters and area were evaluated by the manual 3D-TOE method and by the automatic software. We showed an excellent correlation between the measurements obtained by both methods: intra-class correlation coefficient (ICC): 0.731 (0.508-0.862), r: 0.742 for AA diameter and ICC: 0.723 (0.662-0.923), r: 0.723 for the AA area, with no significant differences regardless of the method used. The interobserver variability was superior for the automatic measurements than for the manual ones. In a subgroup of 10 patients, we also found an excellent correlation between the automatic measurements and those obtained by MDCT, ICC: 0.941 (0.761-0.985), r: 0.901 for AA diameter and ICC: 0.853 (0.409-0.964), r: 0.744 for the AA area.

CONCLUSION

The new automatic 3D-TOE software allows modelling and quantifying the aortic root from 3D-TOE data with high reproducibility. There is good correlation between the automated measurements and other 3D validated techniques. Our results support its use in clinical practice as an alternative to MDCT previous to TAVI.

摘要

目的

最近引入了一种专门的三维经食管超声心动图(3D-TOE)重建工具;该系统根据3D-TOE获取的图像自动构建主动脉根部的几何模型,并对这些结构进行定量分析。本研究的目的是比较新模型获得的主动脉瓣环(AA)测量值与3D-TOE和多排螺旋计算机断层扫描(MDCT)在经导管主动脉瓣植入术(TAVI)候选患者中获得的测量值,并评估这种新方法的可重复性。

方法与结果

我们纳入了31例行TAVI的患者。通过手动3D-TOE方法和自动软件评估AA直径和面积。我们发现两种方法获得的测量值之间具有极好的相关性:组内相关系数(ICC):0.731(0.508 - 0.862),AA直径的r:0.742,AA面积的ICC:0.723(0.662 - 0.923),r:0.723,无论使用何种方法均无显著差异。自动测量的观察者间变异性优于手动测量。在10名患者的亚组中,我们还发现自动测量值与MDCT获得的测量值之间具有极好的相关性,AA直径的ICC:0.941(0.761 - 0.985),r:0.901,AA面积的ICC:0.853(0.409 - 0.964),r:0.744。

结论

新的自动3D-TOE软件能够以高可重复性从3D-TOE数据对主动脉根部进行建模和量化。自动测量值与其他经过3D验证的技术之间具有良好的相关性。我们的结果支持在临床实践中使用它作为TAVI前MDCT的替代方法。

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