Linnet Karen Markussen, Balslev Thomas, Møller-Madsen Bjarne
Børneafdelingen, Aarhus Universitetshospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N.
Ugeskr Laeger. 2015 Aug 10;177(33):V12140712.
Arthrogryposis multiplex congenita (AMC) is a sign rather than a diagnosis. It implies contractures in multiple body areas and occurs in 1:3,000-5,000 live births. Primary aetiologies include neuropathic, myopathic, metabolic, end plate and vascular disorder affecting the developing foetus, including limitation of foetal space. Amyoplasia is the most common type of AMC after central nervous system disorders. Knowledge about the classification of AMC is essential to make a correct diagnosis and treatment plans. We recommend follow-up by experienced paediatric orthopaedic surgeons and neurologists.
先天性多发性关节挛缩症（AMC）是一种体征而非诊断。它意味着多个身体部位出现挛缩，在每3000 - 5000例活产中出现1例。主要病因包括影响发育中胎儿的神经性、肌病性、代谢性、终板和血管性疾病，包括胎儿空间受限。在中枢神经系统疾病之后，缺肢型是AMC最常见的类型。了解AMC的分类对于制定正确的诊断和治疗计划至关重要。我们建议由经验丰富的小儿骨科医生和神经科医生进行随访。
