Mohiuddin Mohammed Khaliq, Chowdavaram Suman, Bogadi Varun, Prabhakar Boddu, Rao Kondadasula Pandu Ranga, Devi Suneetha, Mohan Vasavi
Department of Genetics and Molecular Medicine, Vasavi Medical and Research Centre, Hyderabad, India E-mail :
Asian Pac J Cancer Prev. 2015;16(14):5741-7. doi: 10.7314/apjcp.2015.16.14.5741.
To understand the epidemiology of different upper gastrointestinal (UGI) tract related abnormalities through endoscopic data analysis.
A retrospective study of three years from January 2009 to December 2011 was conducted with data from endoscopic surveillance of upper GI tract problems, collected from the Gastroenterology Unit, Osmania General Hospital, Hyderabad. MS excel and Medcalc software (comparison of proportions) were used for data analysis.
A total of 10,029 (6,468 in males and 3,561 in females) endoscopies were performed during this three-year period. The male to female ratio was 1.8:1. Overall, ~30% of endoscopies evaluated showed patients with acid peptic disorders, 13.6% with vascular- related abnormalities, 10.6% showed structural abnormalities, followed by 6.3% with malignancies. Burden of malignancies was mostly observed in the older age group (60-69 years). Esophageal cancer cases decreased (p=0.0001) whereas stomach cancers increased over this period (p=0.0345). We also observed an increased incidence of acid peptic disease (APD) (p=0.0036) and gastroesophageal reflux disease (GERD) (p=0.0002) cases during this period.
Endoscopic diagnosis is useful for early detection of UGI anomalies and helpful for physicians to manage and treat varied kinds of UGI disorders. Analysis of data revealed changing trends in the incidence of various pathologies of the UGI tract. Functional dyspepsia and GERD definitely reduce the quality of life of the individual. The role of our diverse dietary habits and lifestyle associated with these problems have not yet been established, though there have been reports on the effect of coffee, spicy food, wheat-based diet, screening of UGI pathologies along with collection of complete personal and medical history details, can help in correlating the patients' condition with various aspects of lifestyle and diet.
通过内镜数据分析了解不同上消化道（UGI）相关异常的流行病学情况。
对2009年1月至2011年12月这三年进行回顾性研究，数据来自海得拉巴奥斯曼尼亚总医院胃肠病科对上消化道问题的内镜监测。使用MS excel和Medcalc软件（比例比较）进行数据分析。
在这三年期间共进行了10029例内镜检查（男性6468例，女性3561例）。男女比例为1.8:1。总体而言，约30%接受评估的内镜检查显示患者患有酸相关性消化不良，13.6%患有血管相关异常，10.6%显示结构异常，其次是6.3%患有恶性肿瘤。恶性肿瘤负担主要见于老年组（60 - 69岁）。在此期间，食管癌病例减少（p = 0.0001），而胃癌病例增加（p = 0.0345）。我们还观察到在此期间酸相关性疾病（APD）（p = 0.0036）和胃食管反流病（GERD）（p = 0.0002）病例的发病率增加。
内镜诊断有助于早期发现上消化道异常，有助于医生管理和治疗各种上消化道疾病。数据分析揭示了上消化道各种病理情况发病率的变化趋势。功能性消化不良和胃食管反流病肯定会降低个体的生活质量。尽管有关于咖啡、辛辣食物、以小麦为主的饮食的影响的报道，但与这些问题相关的多样化饮食习惯和生活方式的作用尚未确定。对上消化道疾病进行筛查并收集完整的个人和病史详细信息，有助于将患者的病情与生活方式和饮食的各个方面相关联。
