Xing X
Zhonghua Wai Ke Za Zhi. 1989 Oct;27(10):626-8, 640.
The most frequent cause of failure after tendon transplantation is the formation of adhesions between the tendon graft and its surrounding tissues. In this study, the healing mechanism, adhesion formation and biomechanical properties of vascular pedicle and traditional free tendon grafts were compared in the rabbits. It was observed that the former remained normal histologically in healing process and had less adhesion formation; that of the latter underwent necrosis and was gradually replaced by new connective tissues, its adhesions were extensive and dense; and that the healing mechanism of the both tendon grafts at the anastomosed site were extrinsic, the biomechanical properties (rupture load and elastic stiffness) showed no statistically significant difference (P greater than 0.05). On the basis of these results, we believe that preserving of the blood supply of tendon graft is important for reducing the adhesion formation and improving the functional results.
肌腱移植术后最常见的失败原因是移植肌腱与其周围组织形成粘连。在本研究中,对家兔血管蒂肌腱移植和传统游离肌腱移植的愈合机制、粘连形成及生物力学特性进行了比较。结果观察到,前者在愈合过程中组织学保持正常,粘连形成较少;后者发生坏死并逐渐被新的结缔组织替代,粘连广泛且致密;两种肌腱移植在吻合部位的愈合机制均为外源性,生物力学特性(断裂负荷和弹性刚度)无统计学显著差异(P>0.05)。基于这些结果,我们认为保留移植肌腱的血供对于减少粘连形成和改善功能效果很重要。