Eliacik Mustafa, Karaman Erdur Sevil, Gulkilik Gokhan, Ozsutcu Mustafa, Aras Cengiz, Bayramlar Huseyin, Aslan Cemile Anil
Department of Ophthalmology (M.E., S.K.E., G.G., M.O., C.A., C.A.A.), Istanbul Medipol University School of Medicine, Istanbul, Turkey; and Department of Ophthalmology (H.B.), Medeniyet University School of Medicine, Istanbul, Turkey.
Eye Contact Lens. 2016 Sep;42(5):318-21. doi: 10.1097/ICL.0000000000000185.
To assess changes in anterior-chamber depth (ACD) and angle width after neodymium:yttrium aluminum garnet (Nd:YAG) laser capsulotomy pseudophakia in eyes with pseudoexfoliation (PEX).
This prospective and interventional case series study included 25 pseudophakic eyes of 25 patients with PEX and 26 pseudophakic eyes of 26 patients without PEX scheduled for Nd:YAG laser capsulotomy in a single institution. Anterior-chamber depth and angle width were measured with anterior segment optical coherence tomography before and three days after Nd:YAG laser capsulotomy. Preoperative and postoperative measurements of ACD and angle width included the angle opening distance (AOD), measured as the perpendicular distance from the trabecular meshwork at 500 and 750 mm anterior to the scleral spur to the anterior iris surface (AOD500 and AOD750, respectively) and anterior-chamber angle (ACA) in the nasal and temporal quadrants. Main outcome measures were the changes in ACD and angle width parameters.
The mean ACD, AOD500, AOD750, and ACA (nasal and temporal) measurements were 3.67±0.12 mm, 0.63±0.05 mm and 0.65±0.05 mm, 0.67±0.06 mm and 0.77±0.04 mm, 35.25±1.69° and 35.37±1.68° in eyes with PEX and 3.73±0.11 mm, 0.6±0.05 mm and 0.63±0.05 mm, 0.66±0.06 mm and 0.74±0.06 mm, 34.24±1.6° and 34.6±1.47° in control eyes, respectively (P>0.05 for all). After Nd:YAG laser capsulotomy, mean ACD, AOD500, AOD750, and ACA (nasal and temporal) measurements were 3.76±0.09 mm, 0.73±0.05 mm and 0.76±0.05 mm, 0.75±0.06 mm and 0.87±0.04 mm, 36.82±1.46° and 35.06±1.52° in eyes with PEX and 3.77±0.1 mm, 0.68±0.06 mm and 0.72±0.06 mm, 0.72±0.05 mm and 0.84±0.06 mm, 34.95±1.4° and 35.79±1.36° in control eyes, respectively (P=0.811, P=0.019, P=0.021, P=0.109, P=0.126, P=0.001, and P=0.01, respectively).
The depth and width of the anterior chamber in eyes with PEX and in control eyes increased significantly after Nd:YAG laser capsulotomy. The change in the width of the anterior chamber in eyes PEX was statistically significant comparing control eyes.
评估钕:钇铝石榴石(Nd:YAG)激光晶状体后囊切开术对假性剥脱(PEX)眼人工晶状体眼的前房深度(ACD)和房角宽度的影响。
本前瞻性干预性病例系列研究纳入了在单一机构接受Nd:YAG激光晶状体后囊切开术的25例PEX患者的25只人工晶状体眼和26例非PEX患者的26只人工晶状体眼。在Nd:YAG激光晶状体后囊切开术前及术后3天,使用眼前节光学相干断层扫描测量前房深度和房角宽度。术前和术后ACD和房角宽度的测量包括房角开放距离(AOD),分别测量巩膜突前方500和750μm处小梁网至虹膜前表面的垂直距离(分别为AOD500和AOD750)以及鼻侧和颞侧象限的前房角(ACA)。主要观察指标为ACD和房角宽度参数的变化。
PEX眼的平均ACD、AOD500、AOD750和ACA(鼻侧和颞侧)测量值分别为3.67±0.12mm、0.63±0.05mm和0.65±0.05mm、0.67±0.06mm和0.77±0.04mm、35.25±1.69°和35.37±1.68°,对照眼分别为3.73±0.11mm、0.6±0.05mm和0.63±0.05mm、0.66±0.06mm和0.74±0.06mm、34.24±1.6°和34.6±1.47°(所有P>0.05)。Nd:YAG激光晶状体后囊切开术后,PEX眼的平均ACD、AOD500、AOD750和ACA(鼻侧和颞侧)测量值分别为3.76±0.09mm、0.73±0.05mm和0.76±0.05mm、0.75±0.06mm和0.87±0.04mm、36.82±1.46°和35.06±1.52°,对照眼分别为3.77±0.1mm、0.68±0.06mm和0.72±0.06mm、0.72±0.05mm和0.84±0.06mm、34.95±1.4°和35.79±1.36°(分别为P=0.811、P=0.019、P=0.021、P=0.109、P=0.126、P=0.001和P=0.01)。
Nd:YAG激光晶状体后囊切开术后,PEX眼和对照眼的前房深度和宽度均显著增加。与对照眼相比,PEX眼前房宽度的变化具有统计学意义。