Rezende Maria Lúcia Rubo de, Cunha Paula de Oliveira, Damante Carla Andreotti, Santana Adriana C P, Greghi Sebastião L A, Zangrando Mariana S R
Department of Prosthodontics, Division of Periodontics, Bauru School of Dentistry, University of Sao Paulo, Bauru, Alameda Octavio Pinheiro Brisolla, 9-75/Vila Universitaria, Bauru, SP Zip Code: 17012-901, Brazil, e-mail:
Department of Prosthodontics, Division of Periodontics, Bauru School of Dentistry, University of Sao Paulo, Bauru, SP, Brazil.
J Contemp Dent Pract. 2015 Jun 1;16(6):512-8. doi: 10.5005/jp-journals-10024-1714.
To report a well succeeded use of cyanoacrylate adhesive for fixating a resorbable membrane during a guided tissue regeneration procedure (GTR).
The immobilization of membranes in GTR is essential for establishing proper environment for cell differentiation and tissue regeneration. However, some membranes are very difficult to be kept in position by sutures and its fixation by mini screws or pins may be time consuming and expensive.
A 47-year-old woman presenting a vertical bone defect at the palatal aspect of the left central incisor was treated by GTR using particulate autogenous bone graft associated to a collagen membrane. The membrane was glued to the bone surrounding the defect and to the tooth surface with cyanoacrylate adhesive. The postoperative period was uneventful and 4 years later, excellent results in terms of radiographic filling of the defect and reduction of the probing depth were seen. For illustrative purposes, histological findings obtained during a previous experiment in calvaria of guinea pigs is shown, characterizing a foreign body granuloma and proving that the cyanoacrylate adhesive is a safe tool in GTR.
The use of a membrane glued with cyanoacrylate to immobilize membranes in GTR is viable and safe from both technical and biological standpoints and may be advantageous for clinical and research purposes.
The alternative method for membrane fixation shown in this case report can contribute to simplify the technique in GTR procedures.
报告在引导组织再生术（GTR）中成功使用氰基丙烯酸酯粘合剂固定可吸收膜的情况。
在GTR中固定膜对于建立细胞分化和组织再生的适当环境至关重要。然而，一些膜很难通过缝合固定在位，并且用微型螺钉或销钉固定可能既耗时又昂贵。
一名47岁女性，左中切牙腭侧出现垂直骨缺损，采用GTR治疗，使用颗粒状自体骨移植联合胶原膜。用氰基丙烯酸酯粘合剂将膜粘贴到缺损周围的骨和牙表面。术后过程顺利，4年后，在缺损的影像学填充和探诊深度降低方面取得了优异的结果。为了说明目的，展示了先前在豚鼠颅骨实验中获得的组织学结果，其特征为异物肉芽肿，并证明氰基丙烯酸酯粘合剂在GTR中是一种安全的工具。
从技术和生物学角度来看，在GTR中使用氰基丙烯酸酯粘贴膜来固定膜是可行且安全的，并且可能对临床和研究目的具有优势。
本病例报告中所示的膜固定替代方法有助于简化GTR手术中的技术。
