Sarrión Pérez María Gracia, Bagán José V, Jiménez Yolanda, Margaix María, Marzal Cristina
Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain.
Department of Stomatology (Head of the Department: José V Bagán, MD, DDS, PhD), Faculty of Medicine and Dentistry, University of Valencia, 1 Gascó Oliag Street, 46010, Valencia, Spain; Department of Stomatology and Maxillofacial Surgery (Head of the Department: José V Bagán, MD, DDS, PhD), University General Hospital, 2 Tres Cruces Avenue, 46014, Valencia, Spain.
J Craniomaxillofac Surg. 2015 Nov;43(9):1880-94. doi: 10.1016/j.jcms.2015.07.037. Epub 2015 Aug 7.
Imaging techniques such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) are often used to complement the clinical exploration and staging of oral squamous cell carcinoma (OSCC). Which of these techniques is best in establishing correct staging and treatment planning is not clear, however. This study aims to determine which technique is most appropriate for diagnosing the primary tumor and for detecting bone invasion and neck metastases.
A Medline literature search was made over the last 10 years. In each selected study, we recorded the sample size and sensitivity, specificity and precision. Strengths and limitations of each study were assessed also.
Eight articles relating to detection of the primary tumor, 19 to bone invasion, and 28 to neck metastases were selected and compared.
Despite the high precision of positron emission tomography (PET) or hybrid techniques in detecting the primary tumor, they have not replaced magnetic resonance imaging (MRI) or computed tomography (CT), particularly in the case of small lesions. MRI and CT are adequate techniques in the assessment of bone invasion.Recent studies have shown good results with PET-CT and cone-beam CT, but future studies are needed to demonstrate their benefits. Despite the high precision of PET and PET-CT, their use in assessing neck metastases remains subject to controversy, and their use in all patients with OSCC is not justified. CT and MRI are useful in determining the N category.
磁共振成像（MRI）、计算机断层扫描（CT）和正电子发射断层扫描（PET）等成像技术常被用于辅助口腔鳞状细胞癌（OSCC）的临床检查和分期。然而，这些技术中哪一种最适合用于准确分期和治疗规划尚不清楚。本研究旨在确定哪种技术最适合诊断原发性肿瘤以及检测骨侵犯和颈部转移。
对过去10年的医学文献进行了检索。在每项入选研究中，我们记录了样本量、敏感性、特异性和精确度。同时也评估了每项研究的优势和局限性。
筛选并比较了8篇关于原发性肿瘤检测的文章、19篇关于骨侵犯的文章以及28篇关于颈部转移的文章。
尽管正电子发射断层扫描（PET）或混合技术在检测原发性肿瘤方面具有较高的精确度，但它们尚未取代磁共振成像（MRI）或计算机断层扫描（CT），尤其是在小病灶的情况下。MRI和CT是评估骨侵犯的合适技术。近期研究表明PET-CT和锥形束CT取得了良好的效果，但仍需进一步研究以证明其优势。尽管PET和PET-CT具有较高的精确度，但其在评估颈部转移方面仍存在争议，并非所有OSCC患者都适合使用。CT和MRI在确定N分期方面很有用。
