Bissinger Oliver, Von den Hoff Anne, Maier Elisabeth, Obermeier Katharina Theresa, Stimmer Herbert, Kolk Andreas, Wolff Klaus-Dietrich, Götz Carolin
Department of Oral and Maxillofacial Surgery, Medical University of Innsbruck, Anichstraße 35, 6020 Innsbruck, Austria.
Department of Oral and Maxillofacial Surgery, School of Medicine, Technical University of Munich, Klinikum Rechts der Isar, Ismaninger Str. 22, 81675 Munich, Germany.
Cancers (Basel). 2024 Jan 1;16(1):207. doi: 10.3390/cancers16010207.
The evaluation of surveillance imaging of OSCC patients is a difficult task physicians have to face daily. Multiple patients experience a recurrence of this disease, which underlines the importance of regular patient monitoring programs. Our study analysed the value of surveillance imaging, such as computed tomography (CT) and nuclear magnetic resonance imaging (NMRI), as a patient monitoring programme and its effectiveness in achieving improvement in early recurrence detection. The study comprised 125 patients, out of which 56 ( = 56) showed radiological and 69 ( = 69) showed clinical and radiological conspicuous patterns in domestic follow-ups, respectively. The use of CT and NMRI showed a significant dependence on the histological result ( = 0.03). However, the different groups showed no significant dependence on the histological result ( = 0.96). The distribution of the histological biopsies, which were taken due to radiological changes, were prone to wrong positive diagnoses (false positives) in 71 percent. To conclude, imaging modalities should be chosen for each patient individually to reduce false positives, improve the early detection of recurrence, and increase the cure rate.
对口腔鳞状细胞癌(OSCC)患者的监测成像进行评估是医生每天都必须面对的一项艰巨任务。许多患者会出现这种疾病的复发,这凸显了定期患者监测计划的重要性。我们的研究分析了监测成像(如计算机断层扫描(CT)和核磁共振成像(NMRI))作为患者监测计划的价值及其在早期复发检测方面实现改善的有效性。该研究包括125名患者,其中56名(=56)在国内随访中显示出放射学异常,69名(=69)分别显示出临床和放射学明显异常。CT和NMRI的使用显示出对组织学结果有显著依赖性(=0.03)。然而,不同组对组织学结果没有显著依赖性(=0.96)。因放射学改变而进行的组织学活检分布中,71%容易出现假阳性诊断(误报)。总之,应针对每位患者单独选择成像方式,以减少假阳性、改善复发的早期检测并提高治愈率。